| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Indoleamine 2,3-dioxygenase 2 |
|---|
| Ligand | BDBM50092055 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_885588 (CHEMBL2210857) |
|---|
| IC50 | 18700±n/a nM |
|---|
| Citation |  Bakmiwewa, SM; Fatokun, AA; Tran, A; Payne, RJ; Hunt, NH; Ball, HJ Identification of selective inhibitors of indoleamine 2,3-dioxygenase 2. Bioorg Med Chem Lett22:7641-6 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Indoleamine 2,3-dioxygenase 2 |
|---|
| Name: | Indoleamine 2,3-dioxygenase 2 |
|---|
| Synonyms: | I23O2_MOUSE | IDO-2 | Ido2 | Indol1 | Indoleamine 2,3-dioxygenase-like protein 1 | Indoleamine-pyrrole 2,3-dioxygenase-like protein 1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 45256.34 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_105489 |
|---|
| Residue: | 405 |
|---|
| Sequence: | MEPQSQSMTLEVPLSLGRYHISEEYGFLLPNPLEALPDHYKPWMEIALRLPHLIENRQLR
AHVYRMPLLDCRFLKSYREQRLAHMALAAITMGFVWQEGEGQPQKVLPRSLAIPFVEVSR
NLGLPPILVHSDLVLTNWTKRNPEGPLEISNLETIISFPGGESLRGFILVTVLVEKAAVP
GLKALVQGMEAIRQHSQDTLLEALQQLRLSIQDITRALAQMHDYVDPDIFYSVIRIFLSG
WKDNPAMPVGLVYEGVATEPLKYSGGSAAQSSVLHAFDEFLGIEHCKESVGFLHRMRDYM
PPSHKAFLEDLHVAPSLRDYILASGPGDCLMAYNQCVEALGELRSYHINVVARYIISAAT
RARSRGLTNPSPHALEDRGTGGTAMLSFLKSVREKTMEALLCPGA
|
|
|
|---|
| BDBM50092055 |
|---|
| n/a |
|---|
| Name | BDBM50092055 |
|---|
| Synonyms: | (2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid (4-hydroxy-phenyl)-amide | (2E,4E,6E,8E)-N-(4-hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetraenamide | 3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid (4-hydroxy-phenyl)-amide | 4-hydroxyphenyl retinamide | CHEMBL7301 | FENRETINIDE | N-(4-HYDROXYPHENYL)ALL-TRANS RETINAMIDE | N-(4-hydroxyphenyl)-retinamide | N-(4-hydroxyphenyl)retinamide | N-(4-hydroxyphenyl)retinamide, 4-HPR |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H33NO2 |
|---|
| Mol. Mass. | 391.5457 |
|---|
| SMILES | C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(=O)Nc1ccc(O)cc1 |c:4| |
|---|
| Structure | 
|
|---|
Search and Browse
