| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Indoleamine 2,3-dioxygenase 1 |
|---|
| Ligand | BDBM47032 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_885589 (CHEMBL2210858) |
|---|
| IC50 | 94000±n/a nM |
|---|
| Citation |  Bakmiwewa, SM; Fatokun, AA; Tran, A; Payne, RJ; Hunt, NH; Ball, HJ Identification of selective inhibitors of indoleamine 2,3-dioxygenase 2. Bioorg Med Chem Lett22:7641-6 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Indoleamine 2,3-dioxygenase 1 |
|---|
| Name: | Indoleamine 2,3-dioxygenase 1 |
|---|
| Synonyms: | I23O1_MOUSE | IDO-1 | Ido | Ido1 | Indo | Indoleamine-pyrrole 2,3-dioxygenase |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 45639.39 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_1452149 |
|---|
| Residue: | 407 |
|---|
| Sequence: | MALSKISPTEGSRRILEDHHIDEDVGFALPHPLVELPDAYSPWVLVARNLPVLIENGQLR
EEVEKLPTLSTDGLRGHRLQRLAHLALGYITMAYVWNRGDDDVRKVLPRNIAVPYCELSE
KLGLPPILSYADCVLANWKKKDPNGPMTYENMDILFSFPGGDCDKGFFLVSLLVEIAASP
AIKAIPTVSSAVERQDLKALEKALHDIATSLEKAKEIFKRMRDFVDPDTFFHVLRIYLSG
WKCSSKLPEGLLYEGVWDTPKMFSGGSAGQSSIFQSLDVLLGIKHEAGKESPAEFLQEMR
EYMPPAHRNFLFFLESAPPVREFVISRHNEDLTKAYNECVNGLVSVRKFHLAIVDTYIMK
PSKKKPTDGDKSEEPSNVESRGTGGTNPMTFLRSVKDTTEKALLSWP
|
|
|
|---|
| BDBM47032 |
|---|
| n/a |
|---|
| Name | BDBM47032 |
|---|
| Synonyms: | 2-[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methylsulfinyl]-1H-benzimidazole | 2-[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methylsulfinyl]-1H-benzimidazole | 2-[[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfinyl]-1H-benzimidazole | 2-[[3-methyl-4-[2,2,2-tris(fluoranyl)ethoxy]pyridin-2-yl]methylsulfinyl]-1H-benzimidazole | LANSOPRAZOLE | MLS-0003247.0001 | cid_3883 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H14F3N3O2S |
|---|
| Mol. Mass. | 369.361 |
|---|
| SMILES | Cc1c(OCC(F)(F)F)ccnc1CS(=O)c1nc2ccccc2[nH]1 |
|---|
| Structure | 
|
|---|
Search and Browse
