| Reaction Details |
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 | Report a problem with these data |
| Target | Indoleamine 2,3-dioxygenase 1 |
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| Ligand | BDBM50092055 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_885589 (CHEMBL2210858) |
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| IC50 | 59900±n/a nM |
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| Citation |  Bakmiwewa, SM; Fatokun, AA; Tran, A; Payne, RJ; Hunt, NH; Ball, HJ Identification of selective inhibitors of indoleamine 2,3-dioxygenase 2. Bioorg Med Chem Lett22:7641-6 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Indoleamine 2,3-dioxygenase 1 |
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| Name: | Indoleamine 2,3-dioxygenase 1 |
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| Synonyms: | I23O1_MOUSE | IDO-1 | Ido | Ido1 | Indo | Indoleamine-pyrrole 2,3-dioxygenase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 45639.39 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1452149 |
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| Residue: | 407 |
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| Sequence: | MALSKISPTEGSRRILEDHHIDEDVGFALPHPLVELPDAYSPWVLVARNLPVLIENGQLR
EEVEKLPTLSTDGLRGHRLQRLAHLALGYITMAYVWNRGDDDVRKVLPRNIAVPYCELSE
KLGLPPILSYADCVLANWKKKDPNGPMTYENMDILFSFPGGDCDKGFFLVSLLVEIAASP
AIKAIPTVSSAVERQDLKALEKALHDIATSLEKAKEIFKRMRDFVDPDTFFHVLRIYLSG
WKCSSKLPEGLLYEGVWDTPKMFSGGSAGQSSIFQSLDVLLGIKHEAGKESPAEFLQEMR
EYMPPAHRNFLFFLESAPPVREFVISRHNEDLTKAYNECVNGLVSVRKFHLAIVDTYIMK
PSKKKPTDGDKSEEPSNVESRGTGGTNPMTFLRSVKDTTEKALLSWP
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| BDBM50092055 |
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| n/a |
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| Name | BDBM50092055 |
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| Synonyms: | (2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid (4-hydroxy-phenyl)-amide | (2E,4E,6E,8E)-N-(4-hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetraenamide | 3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid (4-hydroxy-phenyl)-amide | 4-hydroxyphenyl retinamide | CHEMBL7301 | FENRETINIDE | N-(4-HYDROXYPHENYL)ALL-TRANS RETINAMIDE | N-(4-hydroxyphenyl)-retinamide | N-(4-hydroxyphenyl)retinamide | N-(4-hydroxyphenyl)retinamide, 4-HPR |
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| Type | Small organic molecule |
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| Emp. Form. | C26H33NO2 |
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| Mol. Mass. | 391.5457 |
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| SMILES | C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(=O)Nc1ccc(O)cc1 |c:4| |
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| Structure | 
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