| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Ribonuclease pancreatic |
|---|
| Ligand | BDBM50402337 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_885821 (CHEMBL2213779) |
|---|
| Ki | 240±n/a nM |
|---|
| Citation |  Parmenopoulou, V; Chatzileontiadou, DS; Manta, S; Bougiatioti, S; Maragozidis, P; Gkaragkouni, DN; Kaffesaki, E; Kantsadi, AL; Skamnaki, VT; Zographos, SE; Zounpoulakis, P; Balatsos, NA; Komiotis, D; Leonidas, DD Triazole pyrimidine nucleosides as inhibitors of Ribonuclease A. Synthesis, biochemical, and structural evaluation. Bioorg Med Chem20:7184-93 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Ribonuclease pancreatic |
|---|
| Name: | Ribonuclease pancreatic |
|---|
| Synonyms: | CAM-RNase A | RNAS1_BOVIN | RNASE1 | RNAse A | RNS1 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 16468.79 |
|---|
| Organism: | Bison bison (American bison) |
|---|
| Description: | carboxamidomethylated RNase A |
|---|
| Residue: | 150 |
|---|
| Sequence: | MALKSLVLLSLLVLVLLLVRVQPSLGKETAAAKFERQHMDSSTSAASSSNYCNQMMKSRN
LTKDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPN
CAYKTTQANKHIIVACEGNPYVPVHFDASV
|
|
|
|---|
| BDBM50402337 |
|---|
| n/a |
|---|
| Name | BDBM50402337 |
|---|
| Synonyms: | CHEMBL2206660 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H15N5O6 |
|---|
| Mol. Mass. | 325.2774 |
|---|
| SMILES | OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc(Cn2ccc(=O)[nH]c2=O)nn1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
