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TargetNeuropeptide FF receptor 2
LigandBDBM50402447
Substrate/Competitorn/a
Meas. Tech.ChEMBL_886539 (CHEMBL2215248)
Ki 47±n/a nM
Citation Gealageas, R; Schneider, S; Humbert, JP; Bertin, I; Schmitt, M; Laboureyras, E; Dugave, C; Mollereau, C; Simonnet, G; Bourguignon, JJ; Simonin, F; Bihel, F Development of sub-nanomolar dipeptidic ligands of neuropeptide FF receptors. Bioorg Med Chem Lett22:7471-4 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Neuropeptide FF receptor 2
Name:Neuropeptide FF receptor 2
Synonyms:G-protein coupled receptor 74 | G-protein coupled receptor HLWAR77 | GPR74 | NPFF2 | NPFF2_HUMAN | NPFFR2 | NPGPR | Neuropeptide FF receptor 2 | Neuropeptide G-protein coupled receptor
Type:Enzyme Catalytic Domain
Mol. Mass.:60293.78
Organism:Homo sapiens (Human)
Description:NPFF2 0 HUMAN::Q9Y5X5
Residue:522
Sequence:
MNSFFGTPAASWCLLESDVSSAPDKEAGRERRALSVQQRGGPAWSGSLEWSRQSAGDRRR
LGLSRQTAKSSWSRSRDRTCCCRRAWWILVPAADRARRERFIMNEKWDTNSSENWHPIWN
VNDTKHHLYSDINITYVNYYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHT
VTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVA
IAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQN
KTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKN
QEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFA
HWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAKPMEAYALKAKSHVLINTSNQ
LVQESTFQNPHGETLLYRKSAEKPQQELVMEELKETTNSSEI
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50402447
n/a
NameBDBM50402447
Synonyms:CHEMBL2208312
TypeSmall organic molecule
Emp. Form.C25H29N7O3
Mol. Mass.475.5429
SMILES[#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-c1ccc2ccccc2n1)-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#7])=O |r|
Structure
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