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TargetSerine/threonine-protein kinase DCLK3
LigandBDBM50392982
Substrate/Competitorn/a
Meas. Tech.ChEMBL_884734
Kd>10000±n/a nM
Citation Gong LTan YCBoice GAbbot SMcCaleb KIyer PZuo FDal Porto JWong BJin SChang ATran PHsieh GNiu LShao AReuter DLukacs CMUrsula Kammlott RKuglstatter AGoldstein D Discovery of a novel series of 4-quinolone JNK inhibitors. Bioorg Med Chem Lett 22:7381-7 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Serine/threonine-protein kinase DCLK3
Name:Serine/threonine-protein kinase DCLK3
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:73837.68
Organism:Homo sapiens (Human)
Description:ChEMBL_586565
Residue:648
Sequence:
MGKEPLTLKSIQVAVEELYPNKARALTLAQHSRAPSPRLRSRLFSKALKGDHRCGETETP
KSCSEVAGCKAAMRHQGKIPEELSLDDRARTQKKWGRGKWEPEPSSKPPREATLEERHAR
GEKHLGVEIEKTSGEIIRCEKCKRERELQQSLERERLSLGTSELDMGKGPMYDVEKLVRT
RSCRRSPEANPASGEEGWKGDSHRSSPRNPTQELRRPSKSMDKKEDRGPEDQESHAQGAA
KAKKDLVEVLPVTEEGLREVKKDTRPMSRSKHGGWLLREHQAGFEKLRRTRGEEKEAEKE
KKPCMSGGRRMTLRDDQPAKLEKEPKTRPEENKPERPSGRKPRPMGIIAANVEKHYETGR
VIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMVDSEILIIQSLSHPNIVKLHEV
YETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHRDLKP
ENLLVQRNEDKSTTLKLADFGLAKHVVRPIFTVCGTPTYVAPEILSEKGYGLEVDMWAAG
VILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAKDLVSRLLVVDPKK
RYTAHQVLQHPWIETAGKTNTVKRQKQVSPSSEGHFRSQHKRVVEQVS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50392982
n/a
NameBDBM50392982
Synonyms:CHEMBL2152382
TypeSmall organic molecule
Emp. Form.C27H23ClN2O5
Mol. Mass.490.935
SMILESCOC(=O)c1c(Cc2ccc(cc2)C(=O)NCCO)c(=O)c2ccc(Cl)cc2n1-c1ccccc1
Structure
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