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TargetEndoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase
LigandBDBM50169001
Substrate/Competitorn/a
Meas. Tech.ChEMBL_885341
Ki 12040±n/a nM
Citation Moorthy NSBrás NFRamos MJFernandes PA Virtual screening and QSAR study of some pyrrolidine derivatives asa-mannosidase inhibitors for binding feature analysis. Bioorg Med Chem 20:6945-59 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase
Name:Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:79590.42
Organism:Homo sapiens (Human)
Description:ChEMBL_885341
Residue:699
Sequence:
MAACEGRRSGALGSSQSDFLTPPVGGAPWAVATTVVMYPPPPPPPHRDFISVTLSFGENY
DNSKSWRRRSCWRKWKQLSRLQRNMILFLLAFLLFCGLLFYINLADHWKALAFRLEEEQK
MRPEIAGLKPANPPVLPAPQKADTDPENLPEISSQKTQRHIQRGPPHLQIRPPSQDLKDG
TQEEATKRQEAPVDPRPEGDPQRTVISWRGAVIEPEQGTELPSRRAEVPTKPPLPPARTQ
GTPVHLNYRQKGVIDVFLHAWKGYRKFAWGHDELKPVSRSFSEWFGLGLTLIDALDTMWI
LGLRKEFEEARKWVSKKLHFEKDVDVNLFESTIRILGGLLSAYHLSGDSLFLRKAEDFGN
RLMPAFRTPSKIPYSDVNIGTGVAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDKKFQEA
VEKVTQHIHGLSGKKDGLVPMFINTHSGLFTHLGVFTLGARADSYYEYLLKQWIQGGKQE
TQLLEDYVEAIEGVRTHLLRHSEPSKLTFVGELAHGRFSAKMDHLVCFLPGTLALGVYHG
LPASHMELAQELMETCYQMNRQMETGLSPEIVHFNLYPQPGRRDVEVKPADRHNLLRPET
VESLFYLYRVTGDRKYQDWGWEILQSFSRFTRVPSGGYSSINNVQDPQKPEPRDKMESFF
LGETLKYLFLLFSDDPNLLSLDAYVFNTEAHPLPIWTPA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50169001
n/a
NameBDBM50169001
Synonyms:(2R,3R,4S)-2-({[(1S)-2-HYDROXY-1-PHENYLETHYL]AMINO}METHYL)PYRROLIDINE-3,4-DIOL | CHEMBL189366
TypeSmall organic molecule
Emp. Form.C13H20N2O3
Mol. Mass.252.3095
SMILESOC[C@@H](NC[C@H]1NC[C@H](O)[C@@H]1O)c1ccccc1
Structure
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