| Reaction Details |
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 | Report a problem with these data |
| Target | Carnitine O-palmitoyltransferase 1, liver isoform |
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| Ligand | BDBM50403029 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_887531 (CHEMBL2217140) |
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| IC50 | 700±n/a nM |
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| Citation |  Ceccarelli, SM; Chomienne, O; Gubler, M; Arduini, A Carnitine palmitoyltransferase (CPT) modulators: a medicinal chemistry perspective on 35 years of research. J Med Chem54:3109-52 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carnitine O-palmitoyltransferase 1, liver isoform |
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| Name: | Carnitine O-palmitoyltransferase 1, liver isoform |
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| Synonyms: | CPT I | CPT1-L | CPT1A_RAT | CPTI-L | Carnitine O-palmitoyltransferase I, liver isoform | Carnitine palmitoyltransferase 1A | Cpt-1 | Cpt1 | Cpt1a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 88147.11 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_887445 |
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| Residue: | 773 |
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| Sequence: | MAEAHQAVAFQFTVTPDGIDLRLSHEALKQICLSGLHSWKKKFIRFKNGIITGVFPANPS
SWLIVVVGVISSMHAKVDPSLGMIAKISRTLDTTGRMSSQTKNIVSGVLFGTGLWVAVIM
TMRYSLKVLLSYHGWMFAEHGKMSRSTKIWMAMVKVLSGRKPMLYSFQTSLPRLPVPAVK
DTVSRYLESVRPLMKEEDFQRMTALAQDFAVNLGPKLQWYLKLKSWWATNYVSDWWEEYI
YLRGRGPLMVNSNYYAMEMLYITPTHIQAARAGNTIHAILLYRRTLDREELKPIRLLGST
IPLCSAQWERLFNTSRIPGEETDTIQHIKDSRHIVVYHRGRYFKVWLYHDGRLLRPRELE
QQMQQILDDPSEPQPGEAKLAALTAADRVPWAKCRQTYFARGKNKQSLDAVEKAAFFVTL
DESEQGYREEDPEASIDSYAKSLLHGRCFDRWFDKSITFVVFKNSKIGINAEHSWADAPV
VGHLWEYVMATDVFQLGYSEDGHCKGDTNPNIPKPTRLQWDIPGECQEVIDASLSSASLL
ANDVDLHSFPFDSFGKGLIKKCRTSPDAFIQLALQLAHYKDMGKFCLTYEASMTRLFREG
RTETVRSCTMESCNFVQAMMDPKSTAEQRLKLFKIACEKHQHLYRLAMTGAGIDRHLFCL
YVVSKYLAVDSPFLKEVLSEPWRLSTSQTPQQQVELFDFEKNPDYVSCGGGFGPVADDGY
GVSYIIVGENFIHFHISSKFSSPETDSHRFGKHLRQAMMDIITLFGLTINSKK
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| BDBM50403029 |
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| n/a |
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| Name | BDBM50403029 |
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| Synonyms: | CHEMBL2216792 |
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| Type | Small organic molecule |
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| Emp. Form. | C36H53ClN7O19P3S |
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| Mol. Mass. | 1048.281 |
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| SMILES | CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)n1cnc2c(N)cnnc12)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)[C@@]1(CCCCCCOc2ccc(Cl)cc2)CO1 |r| |
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| Structure | 
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