| Reaction Details |
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 | Report a problem with these data |
| Target | Carnitine O-palmitoyltransferase 1, liver isoform |
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| Ligand | BDBM50122839 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_887463 (CHEMBL2217072) |
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| IC50 | 1050±n/a nM |
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| Citation |  Ceccarelli, SM; Chomienne, O; Gubler, M; Arduini, A Carnitine palmitoyltransferase (CPT) modulators: a medicinal chemistry perspective on 35 years of research. J Med Chem54:3109-52 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carnitine O-palmitoyltransferase 1, liver isoform |
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| Name: | Carnitine O-palmitoyltransferase 1, liver isoform |
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| Synonyms: | CPT I | CPT1 | CPT1-L | CPT1A | CPT1A_HUMAN | CPTI-L | Carnitine O-palmitoyltransferase I, liver isoform |
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| Type: | PROTEIN |
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| Mol. Mass.: | 88389.31 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_887463 |
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| Residue: | 773 |
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| Sequence: | MAEAHQAVAFQFTVTPDGIDLRLSHEALRQIYLSGLHSWKKKFIRFKNGIITGVYPASPS
SWLIVVVGVMTTMYAKIDPSLGIIAKINRTLETANCMSSQTKNVVSGVLFGTGLWVALIV
TMRYSLKVLLSYHGWMFTEHGKMSRATKIWMGMVKIFSGRKPMLYSFQTSLPRLPVPAVK
DTVNRYLQSVRPLMKEEDFKRMTALAQDFAVGLGPRLQWYLKLKSWWATNYVSDWWEEYI
YLRGRGPLMVNSNYYAMDLLYILPTHIQAARAGNAIHAILLYRRKLDREEIKPIRLLGST
IPLCSAQWERMFNTSRIPGEETDTIQHMRDSKHIVVYHRGRYFKVWLYHDGRLLKPREME
QQMQRILDNTSEPQPGEARLAALTAGDRVPWARCRQAYFGRGKNKQSLDAVEKAAFFVTL
DETEEGYRSEDPDTSMDSYAKSLLHGRCYDRWFDKSFTFVVFKNGKMGLNAEHSWADAPI
VAHLWEYVMSIDSLQLGYAEDGHCKGDINPNIPYPTRLQWDIPGECQEVIETSLNTANLL
ANDVDFHSFPFVAFGKGIIKKCRTSPDAFVQLALQLAHYKDMGKFCLTYEASMTRLFREG
RTETVRSCTTESCDFVRAMVDPAQTVEQRLKLFKLASEKHQHMYRLAMTGSGIDRHLFCL
YVVSKYLAVESPFLKEVLSEPWRLSTSQTPQQQVELFDLENNPEYVSSGGGFGPVADDGY
GVSYILVGENLINFHISSKFSCPETDSHRFGRHLKEAMTDIITLFGLSSNSKK
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| BDBM50122839 |
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| n/a |
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| Name | BDBM50122839 |
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| Synonyms: | CHEMBL106227 | [3-Carboxy-2-(3-tetradecyl-ureido)-propyl]-trimethyl-ammonium |
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| Type | Small organic molecule |
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| Emp. Form. | C22H45N3O3 |
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| Mol. Mass. | 399.611 |
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| SMILES | CCCCCCCCCCCCCCNC(=O)N[C@H](CC([O-])=O)C[N+](C)(C)C |
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| Structure | 
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