| Reaction Details |
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 | Report a problem with these data |
| Target | Carnitine O-palmitoyltransferase 1, muscle isoform |
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| Ligand | BDBM80613 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_887447 (CHEMBL2217056) |
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| IC50 | 1300±n/a nM |
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| Citation |  Ceccarelli, SM; Chomienne, O; Gubler, M; Arduini, A Carnitine palmitoyltransferase (CPT) modulators: a medicinal chemistry perspective on 35 years of research. J Med Chem54:3109-52 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carnitine O-palmitoyltransferase 1, muscle isoform |
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| Name: | Carnitine O-palmitoyltransferase 1, muscle isoform |
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| Synonyms: | CPT1B_RAT | Carnitine palmitoyltransferase 1B | Cpt1b |
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| Type: | PROTEIN |
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| Mol. Mass.: | 88241.28 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_887447 |
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| Residue: | 772 |
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| Sequence: | MAEAHQAVAFQFTVTPDGVDFRLSREALRHIYLSGINSWKKRLIRIKNGILRGVYPGSPT
SWLVVVMATVGSNYCKVDISMGLVHCIQRCLPTRYGSYGTPQTETLLSMVIFSTGVWATG
IFLFRQTLKLLLSYHGWMFEMHSKTSHATKIWAICVRLLSSRRPMLYSFQTSLPKLPVPS
VPATIHRYLDSVRPLLDDEAYFRMESLAKEFQDKIAPRLQKYLVLKSWWATNYVSDWWEE
YVYLRGRSPIMVNSNYYAMDFVLIKNTSQQAARLGNTVHAMIMYRRKLDREEIKPVMALG
MVPMCSYQMERMFNTTRIPGKETDLLQHLSESRHVAVYHKGRFFKVWLYEGSCLLKPRDL
EMQFQRILDDTSPPQPGEEKLAALTAGGRVEWAEARQKFFSSGKNKMSLDTIERAAFFVA
LDEDSHCYNPDDEASLSLYGKSLLHGNCYNRWFDKSFTLISCKNGQLGLNTEHSWADAPI
IGHLWEFVLATDTFHLGYTETGHCVGEPNTKLPPPQRMQWDIPEQCQTAIENSYQVAKAL
ADDVELYCFQFLPFGKGLIKKCRTSPDAFVQIALQLAHFRDKGKFCLTYEASMTRMFREG
RTETVRSCTSESTAFVRAMMTGSHKKQDLQDLFRKASEKHQNMYRLAMTGAGIDRHLFCL
YIVSKYLGVRSPFLDEVLSEPWSLSTSQIPQFQICMFDPKQYPNHLGAGGGFGPVADHGY
GVSYMIAGENTMFFHVSSKLSSSETNALRFGNHIRQALLDIADLFKISKTDS
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| BDBM80613 |
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| n/a |
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| Name | BDBM80613 |
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| Synonyms: | 1-(2,3,4-Trimethoxy-benzyl)-piperazine | 1-(2,3,4-trimethoxybenzyl)piperazine;hydrochloride | 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine;hydrochloride | MLS001240268 | SMR000674573 | TRIMETAZIDINE | cid_9926449 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H22N2O3 |
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| Mol. Mass. | 266.3361 |
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| SMILES | COc1ccc(CN2CCNCC2)c(OC)c1OC |
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| Structure | 
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