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TargetGag-Pol polyprotein [489-587]
LigandBDBM50403350
Substrate/Competitorn/a
Meas. Tech.ChEBML_157883
Ki 53±n/a nM
Citation Thompson, SKEppley, AMFrazee, JSDarcy, MGLum, RTTomaszek, TAIvanoff, LAMorris, JFSternberg, EJLambert, DMFernandez, AVPetteway, SRMeek, TDMetcalf, BWGleason, JG Synthesis and antiviral activity of a novel class of HIV-1 protease inhibitors containing a heterocyclic P1-P2 amide bond isostere Bioorg Med Chem Lett4:2441-2446 (1994)    Article
More Info.:Get all data from this article,  Assay Method
 
Gag-Pol polyprotein [489-587]
Name:Gag-Pol polyprotein [489-587]
Synonyms:Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:P04585[489-587]
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50403350
n/a
NameBDBM50403350
Synonyms:CHEMBL81190
TypeSmall organic molecule
Emp. Form.C31H41N3O4
Mol. Mass.519.6749
SMILESCCC(C)C(=O)c1cnc([nH]1)[C@@H](C[C@H](O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)Cc1ccccc1
Structure
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