| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H2 receptor |
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| Ligand | BDBM50220423 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_85658 (CHEMBL702650) |
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| Ki | 26915±n/a nM |
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| Citation |  Faghih, R; Dwight, W; Black, L; Liu, H; Gentles, R; Phelan, K; Esbenshade, TA; Ireland, L; Miller, TR; Kang, CH; Krueger, KM; Fox, GB; Hancock, AA; Bennani, YL Structure-activity relationships of non-imidazole H(3) receptor ligands. Part 2: binding preference for D-amino acids motifs. Bioorg Med Chem Lett12:2035-7 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H2 receptor |
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| Name: | Histamine H2 receptor |
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| Synonyms: | Gastric receptor I | H2R | HISTAMINE H2 | HRH2 | HRH2_HUMAN | Histamine H2 receptor | Histamine H2-Gs alpha S |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40115.31 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 359 |
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| Sequence: | MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSL
AITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV
MDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNE
VYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATIREHKATVTLAAVM
GAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQ
QLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGTEVTAPQGATDR
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| BDBM50220423 |
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| n/a |
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| Name | BDBM50220423 |
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| Synonyms: | CHEMBL423666 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H27N3O3 |
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| Mol. Mass. | 357.4467 |
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| SMILES | O=C(C1CC1)c1ccc(OCCCN2CCN(CC2)[C@H]2CC(=O)N2)cc1 |
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| Structure | 
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