| Reaction Details |
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 | Report a problem with these data |
| Target | Substance-K receptor |
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| Ligand | BDBM50404016 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_209210 (CHEMBL818004) |
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| Ki | 0.050119±n/a nM |
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| Citation |  Harmat, NJ; Giannotti, D; Nannicini, R; Perrotta, E; Criscuoli, M; Patacchini, R; Renzetti, AR; Giuliani, S; Altamura, M; Maggi, CA Insertion of 2-carboxysuccinate and tricarballylic acid fragments into cyclic-pseudopeptides: new antagonists for the human tachykinin NK-2 receptor. Bioorg Med Chem Lett12:693-6 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Substance-K receptor |
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| Name: | Substance-K receptor |
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| Synonyms: | NK-2 receptor | NK-2R | NK2R | NK2R_HUMAN | NKNAR | Neurokinin 2 receptor | Neurokinin A receptor | Neurokinin NK2 | Neurokinin-2 (NK-2) | Neuromedin-2 receptor (NK-2R) | SKR | TAC2R | TACR2 | Tachykinin receptor 2 | Tachykinin receptor 2 (NK2) | hnk-3 |
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| Type: | Protein |
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| Mol. Mass.: | 44455.78 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21452 |
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| Residue: | 398 |
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| Sequence: | MGTCDIVTEANISSGPESNTTGITAFSMPSWQLALWATAYLALVLVAVTGNAIVIWIILA
HRRMRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVS
IYSMTAIAADRYMAIVHPFQPRLSAPSTKAVIAGIWLVALALASPQCFYSTVTMDQGATK
CVVAWPEDSGGKTLLLYHLVVIALIYFLPLAVMFVAYSVIGLTLWRRAVPGHQAHGANLR
HLQAMKKFVKTMVLVVLTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMSST
MYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTKEDKLELTPTTSLSTRVNRCHTKETLFMA
GDTAPSEATSGEAGRPQDGSGLWFGYGLLAPTKTHVEI
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| BDBM50404016 |
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| n/a |
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| Name | BDBM50404016 |
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| Synonyms: | CHEMBL2112922 |
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| Type | Small organic molecule |
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| Emp. Form. | C44H53N7O5 |
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| Mol. Mass. | 759.9355 |
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| SMILES | O=C(C1CC(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)CNC1=O)N1CCC(CC1)N1CCCCC1 |
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| Structure | 
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