| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Prothrombin |
|---|
| Ligand | BDBM50404563 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_210578 (CHEMBL816529) |
|---|
| IC50 | 300±n/a nM |
|---|
| Citation |  Kikumoto, R; Tamao, Y; Ohkubo, K; Tezuka, T; Tonomura, S; Okamoto, S; Funahara, Y; Hijikata, A Thrombin inhibitors. 2. Amide derivatives of N alpha-substituted L-arginine. J Med Chem23:830-6 (1980) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Prothrombin |
|---|
| Name: | Prothrombin |
|---|
| Synonyms: | Activation peptide fragment 1 | Activation peptide fragment 2 | Coagulation factor II | F2 | Prothrombin | THRB_BOVIN | Thrombin | Thrombin heavy chain | Thrombin light chain |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 70502.73 |
|---|
| Organism: | Bos taurus (Bovine) |
|---|
| Description: | P00735 |
|---|
| Residue: | 625 |
|---|
| Sequence: | MARVRGPRLPGCLALAALFSLVHSQHVFLAHQQASSLLQRARRANKGFLEEVRKGNLERE
CLEEPCSREEAFEALESLSATDAFWAKYTACESARNPREKLNECLEGNCAEGVGMNYRGN
VSVTRSGIECQLWRSRYPHKPEINSTTHPGADLRENFCRNPDGSITGPWCYTTSPTLRRE
ECSVPVCGQDRVTVEVIPRSGGSTTSQSPLLETCVPDRGREYRGRLAVTTSGSRCLAWSS
EQAKALSKDQDFNPAVPLAENFCRNPDGDEEGAWCYVADQPGDFEYCDLNYCEEPVDGDL
GDRLGEDPDPDAAIEGRTSEDHFQPFFNEKTFGAGEADCGLRPLFEKKQVQDQTEKELFE
SYIEGRIVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNF
TVDDLLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDY
IHPVCLPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERPVCK
ASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGEGCDRD
GKYGFYTHVFRLKKWIQKVIDRLGS
|
|
|
|---|
| BDBM50404563 |
|---|
| n/a |
|---|
| Name | BDBM50404563 |
|---|
| Synonyms: | CHEMBL352975 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H35N5O4S |
|---|
| Mol. Mass. | 513.652 |
|---|
| SMILES | CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1ccc2Oc3ccccc3Cc2c1 |
|---|
| Structure | 
|
|---|
Search and Browse
