| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-1 adrenergic receptor |
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| Ligand | BDBM25761 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_39172 (CHEMBL654469) |
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| Kd | 8.7±n/a nM |
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| Citation |  Lalloz, L; Loppinet, V; Coudert, G; Guillaumet, G; Loubinoux, B; Labrid, C; Beaughard, M; Dureng, G; Lamar, JC 2-Benzodioxinylaminoethanols: a new class of beta-adrenergic blocking and antihypertensive agents. J Med Chem24:994-8 (1982) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Beta-1 adrenergic receptor |
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| Name: | Beta-1 adrenergic receptor |
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| Synonyms: | ADRB1 | Adrenergic receptor | adrenergic Beta1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 50540.48 |
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| Organism: | GUINEA PIG |
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| Description: | adrenergic Beta1 ADRB1 GUINEA PIG::B0FL73 |
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| Residue: | 467 |
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| Sequence: | MGAGVLALGASEPCNLSSTAPLPDGAATAARLLVPASPPASLLPPTSEGSEPLSPQWTAG
MGLLMVLIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVV
WGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARVLVC
TVWAISALVSFLPILMHWWRAEGDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIM
AFVYLRVFREAQKQVKKIDSCERRFLGGPGRPPSPVPSPTPGSPRAATDPLANGRTSKRR
PSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANS
AFNPIIYCRSPDFRKAFQRLLCCARRAARRRHTAHGGRPRASGCLARSGPPPSPGAASDE
DEDAVGAAPPARLLEPWAGCNGGAATADSDWSLDEPGRAGFASESKV
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| BDBM25761 |
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| n/a |
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| Name | BDBM25761 |
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| Synonyms: | Anapriline | Avlocardyl | CHEMBL27 | PROPANOLOL(-) | PROPRANOLOL, d | PROPRANOLOL, l- | PROPRANOLOL,(+) | PROPRANOLOL,(-) | Propanolol | Propanolol,(+/-) | Propranolol | [2-hydroxy-3-(naphthalen-1-yloxy)propyl](propan-2-yl)amine |
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| Type | Small organic molecule |
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| Emp. Form. | C16H21NO2 |
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| Mol. Mass. | 259.3434 |
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| SMILES | CC(C)NCC(O)COc1cccc2ccccc12 |
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| Structure | 
|
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