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TargetMalate dehydrogenase cytoplasmic
LigandBDBM50404708
Substrate/Competitorn/a
Meas. Tech.ChEMBL_52262
IC50 602559.59±n/a nM
Citation Coats EAShah KJMilstein SRGenther CSNene DMRoesener JSchmidt JPleiss MWagner EBaker JK 4-hydroxyquinoline-3-carboxylic acids as inhibitors of cell respiration. 2. Quantitative structure-activity relationship of dehydrogenase enzyme and Ehrlich ascites tumor cell inhibitions. J Med Chem 25:57-63 (1982) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Malate dehydrogenase cytoplasmic
Name:Malate dehydrogenase cytoplasmic
Synonyms:Cytosolic malate dehydrogenase | MDH1 | Malate Dehydrogenase, cytoplasmic
Type:Oxidoreductase; homodimer
Mol. Mass.:36453.77
Organism:Sus scrofa (pig)
Description:Porcine heart cytoplasmic fraction.
Residue:334
Sequence:
MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMELQDC
ALPLLKDVIATDKEEIAFKDLDVAILVGSMPRRDGMERKDLLKANVKIFKCQGAALDKYA
KKSVKVIVVGNPANTNCLTASKSAPSIPKENFSCLTRLDHNRAKAQIALKLGVTSDDVKN
VIIWGNHSSTQYPDVNHAKVKLQAKEVGVYEAVKDDSWLKGEFITTVQQRGAAVIKARKL
SSAMSAAKAICDHVRDIWFGTPEGEFVSMGIISDGNSYGVPDDLLYSFPVTIKDKTWKIV
EGLPINDFSREKMDLTAKELAEEKETAFEFLSSA
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  Blast E-value cutoff:
BDBM50404708
n/a
NameBDBM50404708
Synonyms:CHEMBL160456
TypeSmall organic molecule
Emp. Form.C11H8N2O4
Mol. Mass.232.1922
SMILESNC(=O)c1ccc2c(O)c(cnc2c1)C(O)=O
Structure
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