| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Malate dehydrogenase, cytoplasmic |
|---|
| Ligand | BDBM50404703 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_52262 (CHEMBL665215) |
|---|
| IC50 | 72443.6±n/a nM |
|---|
| Citation |  Coats, EA; Shah, KJ; Milstein, SR; Genther, CS; Nene, DM; Roesener, J; Schmidt, J; Pleiss, M; Wagner, E; Baker, JK 4-hydroxyquinoline-3-carboxylic acids as inhibitors of cell respiration. 2. Quantitative structure-activity relationship of dehydrogenase enzyme and Ehrlich ascites tumor cell inhibitions. J Med Chem25:57-63 (1982) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Malate dehydrogenase, cytoplasmic |
|---|
| Name: | Malate dehydrogenase, cytoplasmic |
|---|
| Synonyms: | Cytosolic malate dehydrogenase | MDH1 | MDHC_PIG | Malate Dehydrogenase, cytoplasmic | Malate dehydrogenase cytoplasmic |
|---|
| Type: | Oxidoreductase; homodimer |
|---|
| Mol. Mass.: | 36453.77 |
|---|
| Organism: | Sus scrofa (pig) |
|---|
| Description: | Porcine heart cytoplasmic fraction. |
|---|
| Residue: | 334 |
|---|
| Sequence: | MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMELQDC
ALPLLKDVIATDKEEIAFKDLDVAILVGSMPRRDGMERKDLLKANVKIFKCQGAALDKYA
KKSVKVIVVGNPANTNCLTASKSAPSIPKENFSCLTRLDHNRAKAQIALKLGVTSDDVKN
VIIWGNHSSTQYPDVNHAKVKLQAKEVGVYEAVKDDSWLKGEFITTVQQRGAAVIKARKL
SSAMSAAKAICDHVRDIWFGTPEGEFVSMGIISDGNSYGVPDDLLYSFPVTIKDKTWKIV
EGLPINDFSREKMDLTAKELAEEKETAFEFLSSA
|
|
|
|---|
| BDBM50404703 |
|---|
| n/a |
|---|
| Name | BDBM50404703 |
|---|
| Synonyms: | CHEMBL155684 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H17NO4 |
|---|
| Mol. Mass. | 359.3747 |
|---|
| SMILES | OC(=O)c1cnc2cc(OCCc3ccc4ccccc4c3)ccc2c1O |
|---|
| Structure | 
|
|---|
Search and Browse
