| Reaction Details |
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 | Report a problem with these data |
| Target | Malate dehydrogenase, mitochondrial |
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| Ligand | BDBM50404727 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_123822 (CHEMBL733653) |
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| IC50 | 478630.09±n/a nM |
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| Citation |  Coats, EA; Shah, KJ; Milstein, SR; Genther, CS; Nene, DM; Roesener, J; Schmidt, J; Pleiss, M; Wagner, E; Baker, JK 4-hydroxyquinoline-3-carboxylic acids as inhibitors of cell respiration. 2. Quantitative structure-activity relationship of dehydrogenase enzyme and Ehrlich ascites tumor cell inhibitions. J Med Chem25:57-63 (1982) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Malate dehydrogenase, mitochondrial |
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| Name: | Malate dehydrogenase, mitochondrial |
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| Synonyms: | MDH2 | MDHM_PIG | Malate dehydrogenase mitochondrial |
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| Type: | Oxidoreductase; homodimer |
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| Mol. Mass.: | 35493.48 |
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| Organism: | Sus scrofa (pig) |
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| Description: | Porcine heart mitochondria. |
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| Residue: | 337 |
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| Sequence: | MLSALARPAGAALRRSFSTSQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHT
PGVAADLSHIETRATVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIV
ATLTAACAQHCPDAMICIISNPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANAFV
AELKGLDPARVSVPVIGGHAGKTIIPLISQCTPKVDFPQDQLSTLTGRIQEAGTEVVKAK
AGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQETDCPYFSTPLLLGKKGIEK
NLGIGKISPFEEKMIAEAIPELKASIKKGEEFVKNMK
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| BDBM50404727 |
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| n/a |
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| Name | BDBM50404727 |
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| Synonyms: | CHEMBL138298 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H12N2O3 |
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| Mol. Mass. | 232.2353 |
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| SMILES | CN(C)c1ccc2c(O)c(cnc2c1)C(O)=O |
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| Structure | 
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