Ki Summary

Reaction Details

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Target

Lutropin-choriogonadotropic hormone receptor

Ligand

BDBM50405765

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_100146 (CHEMBL712503)

204±n/a nM

Citation

Haviv, F; Palabrica, CA; Bush, EN; Diaz, G; Johnson, ES; Love, S; Greer, J Active reduced-size hexapeptide analogues of luteinizing hormone-releasing hormone. J Med Chem32:2340-4 (1989) [PubMed]

More Info.:

Get all data from this article, Assay Method

Lutropin-choriogonadotropic hormone receptor

Name:

Lutropin-choriogonadotropic hormone receptor

Synonyms:

Type:

PROTEIN

Mol. Mass.:

78049.26

Organism:

Rattus norvegicus

Description:

ChEMBL_97289

Residue:

700

Sequence:

MGRRVPALRQLLVLAVLLLKPSQLQSRELSGSRCPEPCDCAPDGALRCPGPRAGLARLSL
TYLPVKVIPSQAFRGLNEVVKIEISQSDSLERIEANAFDNLLNLSELLIQNTKNLLYIEP
GAFTNLPRLKYLSICNTGIRTLPDVTKISSSEFNFILEICDNLHITTIPGNAFQGMNNES
VTLKLYGNGFEEVQSHAFNGTTLISLELKENIYLEKMHSGAFQGATGPSILDISSTKLQA
LPSHGLESIQTLIALSSYSLKTLPSKEKFTSLLVATLTYPSHCCAFRNLPKKEQNFSFSI
FENFSKQCESTVRKADNETLYSAIFEENELSGWDYDYGFCSPKTLQCAPEPDAFNPCEDI
MGYAFLRVLIWLINILAIFGNLTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIA
SVDSQTKGQYYNHAIDWQTGSGCGAAGFFTVFASELSVYTLTVITLERWHTITYAVQLDQ
KLRLRHAIPIMLGGWLFSTLIATMPLVGISNYMKVSICLPMDVESTLSQVYILSILILNV
VAFVVICACYIRIYFAVQNPELTAPNKDTKIAKKMAILIFTDFTCMAPISFFAISAAFKV
PLITVTNSKILLVLFYPVNSCANPFLYAIFTKAFQRDFLLLLSRFGCCKRRAELYRRKEF
SAYTSNCKNGFPGASKPSQATLKLSTVHCQQPIPPRALTH

BDBM50405765

n/a

Name

BDBM50405765

Synonyms:

CHEMBL2369791

Type

Small organic molecule

Emp. Form.

C46H67N11O9

Mol. Mass.

918.0925

SMILES

CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)c1c[nH]c2ccccc12 |wU:5.4,39.40,31.32,23.24,wD:51.53,12.13,(33.1,-17.97,;31.6,-17.59,;31.22,-16.08,;29.74,-15.69,;28.64,-16.77,;29.35,-14.19,;30.32,-13,;29.49,-11.72,;27.98,-12.1,;27.9,-13.64,;26.59,-12.87,;26.6,-11.33,;25.25,-13.64,;25.22,-15.18,;26.56,-15.97,;26.54,-17.51,;27.85,-18.29,;27.84,-19.83,;26.5,-20.57,;29.17,-20.6,;23.91,-12.84,;22.58,-13.64,;22.59,-15.18,;21.24,-12.87,;21.21,-11.33,;22.55,-10.56,;22.53,-9.02,;23.89,-11.3,;19.92,-13.66,;18.57,-12.9,;18.55,-11.36,;17.23,-13.67,;17.26,-15.21,;18.58,-15.98,;19.86,-15.12,;18.76,-17.51,;15.89,-12.93,;14.57,-13.71,;14.57,-15.25,;13.21,-12.94,;13.21,-11.4,;14.54,-10.59,;15.89,-11.36,;17.22,-10.59,;17.2,-9.06,;18.52,-8.27,;15.86,-8.29,;14.53,-9.08,;11.9,-13.73,;10.55,-12.97,;10.53,-11.43,;9.22,-13.76,;9.24,-15.28,;10.56,-16.05,;7.89,-12.99,;6.54,-13.77,;6.55,-15.31,;5.21,-13,;3.8,-13.64,;2.77,-12.52,;3.53,-11.17,;3.05,-9.73,;4.05,-8.57,;5.56,-8.9,;6.04,-10.36,;5.01,-11.49,)|

Structure