Ki Summary

Reaction Details

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Target

Lutropin-choriogonadotropic hormone receptor

Ligand

BDBM50452578

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_100146 (CHEMBL712503)

158±n/a nM

Citation

Haviv, F; Palabrica, CA; Bush, EN; Diaz, G; Johnson, ES; Love, S; Greer, J Active reduced-size hexapeptide analogues of luteinizing hormone-releasing hormone. J Med Chem32:2340-4 (1989) [PubMed]

More Info.:

Get all data from this article, Assay Method

Lutropin-choriogonadotropic hormone receptor

Name:

Lutropin-choriogonadotropic hormone receptor

Synonyms:

Type:

PROTEIN

Mol. Mass.:

78049.26

Organism:

Rattus norvegicus

Description:

ChEMBL_97289

Residue:

700

Sequence:

MGRRVPALRQLLVLAVLLLKPSQLQSRELSGSRCPEPCDCAPDGALRCPGPRAGLARLSL
TYLPVKVIPSQAFRGLNEVVKIEISQSDSLERIEANAFDNLLNLSELLIQNTKNLLYIEP
GAFTNLPRLKYLSICNTGIRTLPDVTKISSSEFNFILEICDNLHITTIPGNAFQGMNNES
VTLKLYGNGFEEVQSHAFNGTTLISLELKENIYLEKMHSGAFQGATGPSILDISSTKLQA
LPSHGLESIQTLIALSSYSLKTLPSKEKFTSLLVATLTYPSHCCAFRNLPKKEQNFSFSI
FENFSKQCESTVRKADNETLYSAIFEENELSGWDYDYGFCSPKTLQCAPEPDAFNPCEDI
MGYAFLRVLIWLINILAIFGNLTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIA
SVDSQTKGQYYNHAIDWQTGSGCGAAGFFTVFASELSVYTLTVITLERWHTITYAVQLDQ
KLRLRHAIPIMLGGWLFSTLIATMPLVGISNYMKVSICLPMDVESTLSQVYILSILILNV
VAFVVICACYIRIYFAVQNPELTAPNKDTKIAKKMAILIFTDFTCMAPISFFAISAAFKV
PLITVTNSKILLVLFYPVNSCANPFLYAIFTKAFQRDFLLLLSRFGCCKRRAELYRRKEF
SAYTSNCKNGFPGASKPSQATLKLSTVHCQQPIPPRALTH

BDBM50452578

n/a

Name

BDBM50452578

Synonyms:

CHEMBL2369793

Type

Small organic molecule

Emp. Form.

C52H69N11O10

Mol. Mass.

1008.172

SMILES

CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)\C=C\c1ccc(OC)cc1 |wU:5.4,31.32,45.48,23.24,wD:57.61,12.13,(32.42,-18.05,;30.95,-17.64,;30.56,-16.16,;29.08,-15.75,;27.97,-16.84,;28.67,-14.27,;29.66,-13.08,;28.82,-11.78,;27.33,-12.16,;27.23,-13.7,;25.91,-12.93,;25.94,-11.39,;24.59,-13.7,;24.57,-15.24,;25.88,-16.04,;25.85,-17.57,;27.2,-18.35,;27.17,-19.89,;25.84,-20.65,;28.5,-20.68,;23.24,-12.92,;21.91,-13.7,;21.94,-15.24,;20.58,-12.95,;20.56,-11.39,;21.88,-10.62,;23.22,-11.38,;21.88,-9.08,;19.25,-13.73,;17.9,-12.96,;17.9,-11.42,;16.59,-13.75,;16.59,-15.29,;17.93,-16.04,;19.34,-15.42,;20.37,-16.55,;19.62,-17.89,;20.11,-19.36,;19.09,-20.5,;17.57,-20.21,;17.09,-18.73,;18.09,-17.58,;15.24,-12.99,;13.91,-13.76,;13.92,-15.3,;12.55,-13.02,;12.55,-11.46,;13.88,-10.69,;15.23,-11.45,;16.55,-10.65,;16.54,-9.12,;17.87,-8.35,;15.21,-8.37,;13.86,-9.15,;11.23,-13.8,;9.89,-13.03,;9.89,-11.49,;8.57,-13.83,;8.57,-15.36,;9.92,-16.1,;7.22,-13.06,;5.88,-13.83,;5.91,-15.39,;4.55,-13.08,;3.22,-13.86,;1.89,-13.09,;.58,-13.86,;-.76,-13.11,;-.79,-11.55,;-2.11,-10.8,;-3.43,-11.58,;.56,-10.78,;1.89,-11.55,)|

Structure