| Reaction Details |
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 | Report a problem with these data |
| Target | 7-dehydrocholesterol reductase |
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| Ligand | BDBM50406617 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_53601 |
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| Ki | 7±n/a nM |
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| Citation |  Ator, MA; Schmidt, SJ; Adams, JL; Dolle, RE; Kruse, LI; Frey, CL; Barone, JM Synthesis, specificity, and antifungal activity of inhibitors of the Candida albicans delta 24-sterol methyltransferase. J Med Chem35:100-6 (1992) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| 7-dehydrocholesterol reductase |
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| Name: | 7-dehydrocholesterol reductase |
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| Synonyms: | DHCR7_RAT | Dhcr7 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 54168.97 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_53595 |
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| Residue: | 471 |
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| Sequence: | MASKSQHNASKAKNHNVKAESQGQWGRAWEVDWFSLVSVIFLLLFAPFIVYYFIMACDQY
SCSLTAPILDVATGRASLADIWAKTPPVTAKAAQLYALWVSFQVLLYSWLPDFCHRFLPG
YVGGVQEGAITPAGIVNKYEVNGLQAWLITHFLWFVNAYLLSWFSPTIIFDNWIPLLWCA
NILGYAVSTFAMIKGYLFPTSAEDCKFTGNFFYNYMMGIEFNPRIGKWFDFKLFFNGRPG
IVAWTLINLSFAAKQQELYGHVTNSMILVNVLQAIYVLDFFWNETWYLKTIDICHDHFGW
YLGWGDCVWLPYLYTLQGLYLVYHPVQLSTPNALGVLLLGLVGYYIFRMTNHQKDLFRRT
DGHCLIWGKKPKAIECSYTSADGLKHRSKLLVSGFWGVARHFNYTGDLMGSLAYCLACGG
GHLLPYFYIIYMTILLTHRCLRDEHRCANKYGRDWERYVAAVPYRLLPGIF
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| BDBM50406617 |
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| n/a |
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| Name | BDBM50406617 |
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| Synonyms: | CHEMBL276388 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H46N2O |
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| Mol. Mass. | 414.6669 |
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| SMILES | C[C@H](CCC(N)=N)C1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]1(C)CC[C@H](O)C(C)(C)C1CC3 |r,c:12| |
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| Structure | 
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