| Reaction Details |
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 | Report a problem with these data |
| Target | Steroid 5-alpha-reductase |
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| Ligand | BDBM50407316 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_204747 |
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| Ki | 22±n/a nM |
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| Citation |  Holt DA; Yamashita DS; Konialian-Beck AL; Luengo JI; Abell AD; Bergsma DJ; Brandt M; Levy MA Benzophenone- and indolecarboxylic acids: potent type-2 specific inhibitors of human steroid 5 alpha-reductase. J Med Chem 38:13-5 (1995) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Steroid 5-alpha-reductase |
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| Name: | Steroid 5-alpha-reductase |
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| Synonyms: | 3-oxo-5-alpha-steroid 4-dehydrogenase 2 | 5 alpha-SR2 | 5α-Reductase 2 (5α-R2) | SR type 2 | Steroid 5-alpha-reductase 2 | Type II 5-alpha reductase |
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| Type: | Enzyme |
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| Mol. Mass.: | 28406.59 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P31213 |
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| Residue: | 254 |
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| Sequence: | MQVQCQQSPVLAGSATLVALGALALYVAKPSGYGKHTESLKPAATRLPARAAWFLQELPS
FAVPAGILARQPLSLFGPPGTVLLGLFCVHYFHRTFVYSLLNRGRPYPAILILRGTAFCT
GNGVLQGYYLIYCAEYPDGWYTDIRFSLGVFLFILGMGINIHSDYILRQLRKPGEISYRI
PQGGLFTYVSGANFLGEIIEWIGYALATWSLPALAFAFFSLCFLGLRAFHHHRFYLKMFE
DYPKSRKALIPFIF
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| BDBM50407316 |
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| n/a |
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| Name | BDBM50407316 |
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| Synonyms: | CHEMBL286372 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H14O5 |
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| Mol. Mass. | 346.3329 |
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| SMILES | OC(=O)c1ccc(cc1)C(=O)c1ccc(cc1)C(=O)c1ccc(O)cc1 |
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| Structure | 
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