| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2C |
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| Ligand | BDBM84991 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2774 (CHEMBL858023) |
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| Ki | 1514±n/a nM |
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| Citation |  Audia, JE; Evrard, DA; Murdoch, GR; Droste, JJ; Nissen, JS; Schenck, KW; Fludzinski, P; Lucaites, VL; Nelson, DL; Cohen, ML Potent, selective tetrahydro-beta-carboline antagonists of the serotonin 2B (5HT2B) contractile receptor in the rat stomach fundus. J Med Chem39:2773-80 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 2C |
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| Name: | 5-hydroxytryptamine receptor 2C |
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| Synonyms: | 5-HT2C | 5-hydroxytryptamine receptor 2C | 5-hydroxytryptamine receptor 2C (5HT2C) | 5HT2C_MOUSE | 5ht1c | Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor | Htr1c | Htr2c | Serotonin 2c (5-HT2c) receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 51948.16 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | P34968 |
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| Residue: | 459 |
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| Sequence: | MVNLGTAVRSLLVHLIGLLVWQFDISISPVAAIVTDTFNSSDGGRLFQFPDGVQNWPALS
IVVIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYV
WPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVW
AISIGVSVPIPVIGLRDESKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYFLTIY
VLRRQTLMLLRGHTEEELRNISLNFLKCCCKKGDEEENAPNPNPDQKPRRKKKEKRPRGT
MQAINNEKKASKVLGIVFFVFLIMWCPFFITNILSVLCGKACNQKLMEKLLNVFVWIGYV
CSGINPLVYTLFNKIYRRAFSKYLRCDYKPDKKPPVRQIPRVAATALSGRELNVNIYRHT
NERVVRKANDTEPGIEMQVENLELPVNPSNVVSERISSV
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| BDBM84991 |
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| n/a |
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| Name | BDBM84991 |
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| Synonyms: | CAS_3277600 | NSC_3277600 | SB204741 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H14N4OS |
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| Mol. Mass. | 286.352 |
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| SMILES | Cc1cc(NC(=O)Nc2ccc3n(C)ccc3c2)sn1 |
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| Structure | 
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