| Reaction Details |
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 | Report a problem with these data |
| Target | Neuronal acetylcholine receptor subunit alpha-9 |
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| Ligand | BDBM50408547 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_142899 (CHEMBL748708) |
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| Kd | 0.045±n/a nM |
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| Citation |  Horti, AG; Scheffel, U; Kimes, AS; Musachio, JL; Ravert, HT; Mathews, WB; Zhan, Y; Finley, PA; London, ED; Dannals, RF Synthesis and evaluation of N-[11C]methylated analogues of epibatidine as tracers for positron emission tomographic studies of nicotinic acetylcholine receptors. J Med Chem41:4199-206 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuronal acetylcholine receptor subunit alpha-9 |
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| Name: | Neuronal acetylcholine receptor subunit alpha-9 |
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| Synonyms: | ACHA9_RAT | Acra9 | Cholinergic, Nicotinic Muscle | Chrna9 | NACHR alpha 9 | Neuronal acetylcholine receptor subunit alpha-9 | Nicotinic acetylcholine receptor subunit alpha 9 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 54522.69 |
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| Organism: | RAT |
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| Description: | Cholinergic, Nicotinic Muscle 0 RAT::P43144 |
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| Residue: | 479 |
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| Sequence: | MNRPHSCLSFCWMYFAASGIRAVETANGKYAQKLFSDLFEDYSSALRPVEDTDAVLNVTL
QVTLSQIKDMDERNQILTAYLWIRQTWHDAYLTWDRDQYDRLDSIRIPSDLVWRPDIVLY
NKADDESSEPVNTNVVLRYDGLITWDSPAITKSSCVVDVTYFPFDSQQCNLTFGSWTYNG
NQVDIFNALDSGDLSDFIEDVEWEVHGMPAVKNVISYGCCSEPYPDVTFTLLLKRRSSFY
IVNLLIPCVLISFLAPLSFYLPAASGEKVSLGVTILLAMTVFQLMVAEIMPASENVPLIG
KYYIATMALITASTALTIMVMNIHFCGAEARPVPHWAKVVILKYMSRILFVYDVGESCLS
PRHSQEPEQVTKVYSKLPESNLKTSRNKDLSRKKEVRKLLKNDLGYQGGIPQNTDSYCAR
YEALTKNIEYIAKCLKDHKATNSKGSEWKKVAKVIDRFFMWIFFAMVFVMTVLIIARAD
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| BDBM50408547 |
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| n/a |
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| Name | BDBM50408547 |
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| Synonyms: | CHEMBL135684 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H14BrN |
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| Mol. Mass. | 252.15 |
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| SMILES | Brc1ccc(cc1)C1CC2CCC1N2 |THB:4:7:13:11.10| |
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| Structure | 
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