| Reaction Details |
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 | Report a problem with these data |
| Target | Melatonin receptor type 1A |
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| Ligand | BDBM29611 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_105108 (CHEMBL856174) |
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| IC50 | 1±n/a nM |
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| Citation |  Marot, C; Chavatte, P; Morin-Allory, L; Viaud, MC; Guillaumet, G; Renard, P; Lesieur, D; Michel, A Pharmacophoric search and 3D-QSAR comparative molecular field analysis studies on agonists of melatonin sheep receptors. J Med Chem41:4453-65 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melatonin receptor type 1A |
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| Name: | Melatonin receptor type 1A |
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| Synonyms: | MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A |
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| Type: | Enzyme |
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| Mol. Mass.: | 39392.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P48039 |
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| Residue: | 350 |
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| Sequence: | MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA
QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
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| BDBM29611 |
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| n/a |
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| Name | BDBM29611 |
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| Synonyms: | 2-Iodomelatonin | CHEMBL289233 | Melatonin,2-Iodo |
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| Type | Small organic molecule |
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| Emp. Form. | C13H15IN2O2 |
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| Mol. Mass. | 358.1749 |
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| SMILES | COc1ccc2[nH]c(I)c(CCNC(C)=O)c2c1 |
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| Structure | 
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