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TargetHistidine-rich protein
LigandBDBM23300
Substrate/Competitorn/a
Meas. Tech.ChEMBL_155111
IC50 16000±n/a nM
Citation Vippagunta SRDorn AMatile HBhattacharjee AKKarle JMEllis WYRidley RGVennerstrom JL Structural specificity of chloroquine-hematin binding related to inhibition of hematin polymerization and parasite growth. J Med Chem 42:4630-9 (1999) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Histidine-rich protein
Name:Histidine-rich protein
Synonyms:Histidine-rich protein PFHRP-II
Type:PROTEIN
Mol. Mass.:35156.49
Organism:Plasmodium falciparum
Description:ChEMBL_500704
Residue:332
Sequence:
MVSFSKNKVLSAAVFASVLLLDNNNSAFNNNLCSKNAKGLNLNKRLLHETQAHVDDAHHA
HHVADAHHAHHAHHAADAHHAHHAADAHHAHHAADAHHAHHAADAHHAHHAADAHHAHHA
ADAHHAHHAADAHHAHHAADAHHAHHAADAHHAHHAAYAHHAHHASDAHHAADAHHAAYA
HHAHHAADAHHAADAHHAAYAHHAHHAADAHHAADAHHATDAHHAHHAADAHHATDAHHA
ADAHHAADAHHATDAHHAADAHHATDAHHAADAHHAADAHHATDSHHAHHAADAHHAAAH
HATDAHHAAAHHATDAHHAAAHHEAATHCLRH
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  Blast E-value cutoff:
BDBM23300
n/a
NameBDBM23300
Synonyms:4-amino-7-chloroquinoline (ACQ)-based compound, 5 | 7-chloroquinolin-4-amine | CHEMBL44789
TypeSmall organic molecule
Emp. Form.C9H7ClN2
Mol. Mass.178.618
SMILESNc1ccnc2cc(Cl)ccc12
Structure
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