| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50455440 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_158030 (CHEMBL768621) |
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| IC50 | 39±n/a nM |
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| Citation |  Vieth, M; Cummins, DJ DoMCoSAR: a novel approach for establishing the docking mode that is consistent with the structure-activity relationship. Application to HIV-1 protease inhibitors and VEGF receptor tyrosine kinase inhibitors. J Med Chem43:3020-32 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
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|
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| BDBM50455440 |
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| n/a |
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| Name | BDBM50455440 |
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| Synonyms: | CHEMBL2367850 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H40N2O5 |
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| Mol. Mass. | 532.6704 |
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| SMILES | [H][C@](O)(C[C@@]([H])(Cc1ccccc1)C(=O)N[C@H](CO)c1ccccc1)[C@]([H])(Cc1ccccc1)NC(=O)OC(C)(C)C |
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| Structure | 
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