| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] A |
|---|
| Ligand | BDBM50378564 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_123580 (CHEMBL732300) |
|---|
| IC50 | 6760.83±n/a nM |
|---|
| Citation |  Gnerre, C; Catto, M; Leonetti, F; Weber, P; Carrupt, PA; Altomare, C; Carotti, A; Testa, B Inhibition of monoamine oxidases by functionalized coumarin derivatives: biological activities, QSARs, and 3D-QSARs. J Med Chem43:4747-58 (2000) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Amine oxidase [flavin-containing] A |
|---|
| Name: | Amine oxidase [flavin-containing] A |
|---|
| Synonyms: | AOFA_RAT | Amine oxidase (flavin-containing) A | Amine oxidase [flavin-containing] A | Maoa | Monoamine Oxidase Type A (MAO-A) | Monoamine oxidase | Monoamine oxidase A (MAO-A) | Monoamine oxidase A (rMAO-A) | Monoamine oxidase type A (MAOA) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 59515.21 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | n/a |
|---|
| Residue: | 526 |
|---|
| Sequence: | MTDLEKPNLAGHMFDVGLIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHV
KWVDVGGAYVGPTQNRILRLSKELGIETYKVNVNERLVQYVKGKTYPFRGAFPPVWNPLA
YLDYNNLWRTMDEMGKEIPVDAPWQARHAQEWDKMTMKDLIDKICWTKTAREFAYLFVNI
NVTSEPHEVSALWFLWYVRQCGGTARIFSVTNGGQERKFVGGSGQVSEQIMGLLGDKVKL
SSPVTYIDQTDDNIIVETLNHEHYECKYVISAIPPILTAKIHFKPELPPERNQLIQRLPM
GAVIKCMVYYKEAFWKKKDYCGCMIIEDEEAPIAITLDDTKPDGSLPAIMGFILARKADR
QAKLHKDIRKRKICELYAKVLGSQEALYPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYG
RVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVLNALGKVAKKDIWVEEPESKD
VPAIEITHTFLERNLPSVPGLLKITGVSTSVALLCFVLYKIKKLPC
|
|
|
|---|
| BDBM50378564 |
|---|
| n/a |
|---|
| Name | BDBM50378564 |
|---|
| Synonyms: | CHEMBL145781 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H12O3 |
|---|
| Mol. Mass. | 252.2647 |
|---|
| SMILES | O=c1ccc2ccc(OCc3ccccc3)cc2o1 |
|---|
| Structure | 
|
|---|
Search and Browse
