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TargetBeta-2 adrenergic receptor
LigandBDBM50409481
Substrate/Competitorn/a
Meas. Tech.ChEMBL_218263 (CHEMBL819428)
IC50 2187.76±n/a nM
Citation Tanaka, NTamai, TMukaiyama, HHirabayashi, AMuranaka, HAkahane, SMiyata, HAkahane, M Discovery of novel N-phenylglycine derivatives as potent and selective beta(3)-adrenoceptor agonists for the treatment of frequent urination and urinary incontinence. J Med Chem44:1436-45 (2001) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Beta-2 adrenergic receptor
Name:Beta-2 adrenergic receptor
Synonyms:ADRB2_RAT | Adrb2 | Adrb2r | Adrenergic receptor beta
Type:PROTEIN
Mol. Mass.:46896.26
Organism:Rattus norvegicus
Description:ChEMBL_38603
Residue:418
Sequence:
MEPHGNDSDFLLAPNGSRAPGHDITQERDEAWVVGMAILMSVIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWNFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYVAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHKQ
AIDCYAKETCCDFFTNQAYAIASSIVSFYVPLVVMVFVYSRVFQVAKRQLQKIDKSEGRF
HAQNLSQVEQDGRSGHGLRSSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIRA
NLIPKEVYILLNWLGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSSKTYGNGYSSNSNG
RTDYTGEQSAYQLGQEKENELLCEEAPGMEGFVNCQGTVPSLSIDSQGRNCNTNDSPL
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  Blast E-value cutoff:
BDBM50409481
n/a
NameBDBM50409481
Synonyms:CHEMBL35738
TypeSmall organic molecule
Emp. Form.C19H23IN2O4
Mol. Mass.470.3014
SMILESC[C@H](NCCc1ccc(NCC(O)=O)c(I)c1)[C@H](O)c1ccc(O)cc1
Structure
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