| Reaction Details |
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 | Report a problem with these data |
| Target | Carboxylic ester hydrolase |
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| Ligand | BDBM50409662 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_92659 (CHEMBL877911) |
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| IC50 | 10000±n/a nM |
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| Citation |  Wheelock, CE; Colvin, ME; Uemura, I; Olmstead, MM; Sanborn, JR; Nakagawa, Y; Jones, AD; Hammock, BD Use of ab initio calculations to predict the biological potency of carboxylesterase inhibitors. J Med Chem45:5576-93 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Carboxylic ester hydrolase |
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| Name: | Carboxylic ester hydrolase |
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| Synonyms: | CG8425-PA [Drosophila melanogaster] |
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| Type: | PROTEIN |
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| Mol. Mass.: | 64506.23 |
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| Organism: | Drosophila melanogaster |
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| Description: | ChEMBL_92659 |
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| Residue: | 579 |
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| Sequence: | MIQQRMLQLLLLGQLLAGPGPFCAALATVDQLTVCPPSVGCLKGTNLQGYQSERFEAFMG
IPYALPPIGDLRFSNPKVMPKLLGMYDASAPKMDCIQKNYLLPTPVVYGDEDCLYLNVYR
PEIRKSALPVMVYIHGGGFFGGSAGPGVTGPEYFMDSGEVILVTMAYRLGPFGFLSTQDA
VMSGNFGLKDQNLALRWVQRNIRFFGGDPQRVTIFGQSAGGVAAHMHLLSPRSHGLFHRV
ISMSGTANVPFAIAEQPLEQARLLAEFADVPDARNLSTVKLTKALRRINATKLLNAGDGL
KYWDVDHMTNFRPVVEEGLEVDAFLNAHPMDMLAQGMPTSIPLLLGTVPGEGAVRVVNIL
GNETLRQSFNLRFDELLQELLEFPASFSQDRREKMMDLLVEVYFQGQHEVNELTVQGFMN
LISDRGFKQPLYNTIHKNVCHTPNPVYLYSFNYQGPLSYASAYTSANVTGKYGVVHCDDL
LYLFRSPLLFPDFQRNSTEAKVIHSFVDYFVHFAKFGKPRNSESLTPCSIEVLQSRPDGI
CDYHEFANAPDAYQGFEVHVASEFQTDRVNLWSHILNEK
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| BDBM50409662 |
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| n/a |
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| Name | BDBM50409662 |
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| Synonyms: | CHEMBL152698 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H18F2O |
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| Mol. Mass. | 192.2461 |
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| SMILES | CCCCCCCCC(=O)C(F)F |
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| Structure | 
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