| Reaction Details |
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 | Report a problem with these data |
| Target | Acylcarnitine hydrolase |
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| Ligand | BDBM50371962 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_216226 (CHEMBL823860) |
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| IC50 | 446.68±n/a nM |
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| Citation |  Wheelock, CE; Colvin, ME; Uemura, I; Olmstead, MM; Sanborn, JR; Nakagawa, Y; Jones, AD; Hammock, BD Use of ab initio calculations to predict the biological potency of carboxylesterase inhibitors. J Med Chem45:5576-93 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Acylcarnitine hydrolase |
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| Name: | Acylcarnitine hydrolase |
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| Synonyms: | Carboxylesterase 2 | Ces2 | Ces2c | EST2C_MOUSE |
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| Type: | PROTEIN |
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| Mol. Mass.: | 62457.35 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_216226 |
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| Residue: | 561 |
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| Sequence: | MTRNQLHNWLNAGFFGLLLLLIHVQGQDSPEANPIRNTHTGQIQGSLIHVKDTKAGVHTF
LGIPFAKPPVGPLRFAPPEAPEPWSGVRDGTAHPAMCLQNLDMLNEAGLPDMKMMLSSFP
MSEDCLYLNIYTPAHAHEGSNLPVMVWIHGGALVIGMASMFDGSLLTVNEDLVVVTIQYR
LGVLGFFSTGDQHARGNWGYLDQAAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSHV
VSPMSQGLFHGAIMESGVALLPDLISETSEMVSTTVAKLSGCEAMDSQALVRCLRGKSEA
EILAINKVFKMIPAVVDGEFFPRHPKELLASEDFHPVPSIIGVNNDEFGWSIPVVMGSAQ
MIKGITRENLQAVLKDTAVQMMLPPECSDLLMEEYMGDTEDAQTLQIQFTEMMGDFMFVI
PALQVAHFQRSHAPVYFYEFQHPPSYFKDVRPPHVKADHADEIPFVFASFFWGMKLDFTE
EEELLSRRMMKYWANFARHGNPNSEGLPYWPVMDHDEQYLQLDIQPAVGRALKAGRLQFW
TKTLPQKIQELKASQDKHREL
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| BDBM50371962 |
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| n/a |
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| Name | BDBM50371962 |
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| Synonyms: | CHEMBL155396 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H15F3O2S |
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| Mol. Mass. | 244.274 |
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| SMILES | CCCCCCS(=O)CC(=O)C(F)(F)F |
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| Structure | 
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