| Reaction Details |
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 | Report a problem with these data |
| Target | Integrase |
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| Ligand | BDBM50409838 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_88770 (CHEMBL701802) |
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| IC50 | 6025.6±n/a nM |
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| Citation |  Kuo, CL; Assefa, H; Kamath, S; Brzozowski, Z; Slawinski, J; Saczewski, F; Buolamwini, JK; Neamati, N Application of CoMFA and CoMSIA 3D-QSAR and docking studies in optimization of mercaptobenzenesulfonamides as HIV-1 integrase inhibitors. J Med Chem47:385-99 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Integrase |
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| Name: | Integrase |
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| Synonyms: | Human immunodeficiency virus type 1 integrase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32231.48 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | ChEMBL_90865 |
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| Residue: | 288 |
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| Sequence: | FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
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| BDBM50409838 |
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| n/a |
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| Name | BDBM50409838 |
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| Synonyms: | CHEMBL127330 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H15Cl2N5O3S2 |
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| Mol. Mass. | 520.411 |
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| SMILES | Sc1cc(Cl)c(cc1S(=O)(=O)Nc1nncn1-c1ccc(Cl)cc1)C(=O)Nc1ccccc1 |
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| Structure | 
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