| Reaction Details |
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 | Report a problem with these data |
| Target | RNA-directed RNA polymerase |
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| Ligand | BDBM50410391 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_302873 (CHEMBL828787) |
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| Ki | 229000±n/a nM |
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| Citation |  Koh, YH; Shim, JH; Wu, JZ; Zhong, W; Hong, Z; Girardet, JL Design, synthesis, and antiviral activity of adenosine 5'-phosphonate analogues as chain terminators against hepatitis C virus. J Med Chem48:2867-75 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| RNA-directed RNA polymerase |
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| Name: | RNA-directed RNA polymerase |
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| Synonyms: | Hepatitis C virus NS5B RNA-dependent RNA polymerase | NS5B protein |
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| Type: | Protein |
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| Mol. Mass.: | 25173.95 |
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| Organism: | Hepatitis C virus |
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| Description: | Q8JXU8 |
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| Residue: | 229 |
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| Sequence: | RTEEAIYQCCDLDPQARVAIRSLTERLYVGGPLTNSRGENCGYRRRASGVLTTSCGNTLT
CYIKAQAACRAAGRQDCTMLVCGDDLVVICESAGVQEDAASLRAFTEAMTRYSAPPGDPP
QPEYDLELITSCSSNVSVAHDGAGKRVYYLTRDPTTPLARAAWETARHTPVNSWLGNIIM
FAPTLWVRMIMLTHFFSVLIARDQLEQALDCEIYGACYSIEPLLPPIIQ
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| BDBM50410391 |
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| n/a |
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| Name | BDBM50410391 |
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| Synonyms: | CHEMBL1161753 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H20N5O12P3 |
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| Mol. Mass. | 507.2241 |
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| SMILES | Nc1ncnc2n(cnc12)[C@@H]1C[C@H](OCP(O)(=O)OP(O)(=O)OP(O)(O)O)[C@@H](O)[C@H]1O |r| |
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| Structure | 
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