| Reaction Details |
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 | Report a problem with these data |
| Target | Histidine-rich protein PFHRP-II |
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| Ligand | BDBM50176388 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_328025 (CHEMBL863915) |
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| IC50 | 50000±n/a nM |
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| Citation |  Melnyk, P; Leroux, V; Sergheraert, C; Grellier, P Design, synthesis and in vitro antimalarial activity of an acylhydrazone library. Bioorg Med Chem Lett16:31-5 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histidine-rich protein PFHRP-II |
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| Name: | Histidine-rich protein PFHRP-II |
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| Synonyms: | HRP1_PLAFA | Histidine-rich protein | Histidine-rich protein PFHRP-II |
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| Type: | PROTEIN |
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| Mol. Mass.: | 35156.49 |
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| Organism: | Plasmodium falciparum |
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| Description: | ChEMBL_500704 |
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| Residue: | 332 |
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| Sequence: | MVSFSKNKVLSAAVFASVLLLDNNNSAFNNNLCSKNAKGLNLNKRLLHETQAHVDDAHHA
HHVADAHHAHHAHHAADAHHAHHAADAHHAHHAADAHHAHHAADAHHAHHAADAHHAHHA
ADAHHAHHAADAHHAHHAADAHHAHHAADAHHAHHAAYAHHAHHASDAHHAADAHHAAYA
HHAHHAADAHHAADAHHAAYAHHAHHAADAHHAADAHHATDAHHAHHAADAHHATDAHHA
ADAHHAADAHHATDAHHAADAHHATDAHHAADAHHAADAHHATDSHHAHHAADAHHAAAH
HATDAHHAAAHHATDAHHAAAHHEAATHCLRH
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| BDBM50176388 |
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| n/a |
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| Name | BDBM50176388 |
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| Synonyms: | CHEMBL199543 | N'-(2-hydroxy-5-methylbenzylidene)-4-tert-butylbenzohydrazide |
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| Type | Small organic molecule |
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| Emp. Form. | C19H22N2O2 |
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| Mol. Mass. | 310.3902 |
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| SMILES | Cc1ccc(O)c(C=NNC(=O)c2ccc(cc2)C(C)(C)C)c1 |w:7.6| |
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| Structure | 
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