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TargetAdenosine receptor A2b
LigandBDBM50410644
Substrate/Competitorn/a
Meas. Tech.ChEMBL_330270
Ki 3.55±n/a nM
Citation Carotti ACadavid MICenteno NBEsteve CLoza MIMartinez ANieto RRaviña ESanz FSegarra VSotelo EStefanachi AVidal B Design, synthesis, and structure-activity relationships of 1-,3-,8-, and 9-substituted-9-deazaxanthines at the human A2B adenosine receptor. J Med Chem 49:282-99 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Adenosine receptor A2b
Name:Adenosine receptor
Synonyms:ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B)
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:36341.22
Organism:Homo sapiens (Human)
Description:n/a
Residue:332
Sequence:
MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
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  Blast E-value cutoff:
BDBM50410644
n/a
NameBDBM50410644
Synonyms:CHEMBL439868
TypeSmall organic molecule
Emp. Form.C24H22N4O5
Mol. Mass.446.4553
SMILESCC(=O)c1ccc(NC(=O)COc2ccc(cc2)-c2cc3n(C)c(=O)n(C)c(=O)c3[nH]2)cc1
Structure
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