| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cathepsin K |
|---|
| Ligand | BDBM50374296 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_365368 (CHEMBL871198) |
|---|
| Ki | 3.3±n/a nM |
|---|
| Citation |  Palmer, JT; Hirschbein, BL; Cheung, H; McCarter, J; Janc, JW; Yu, ZW; Wesolowski, G Keto-1,3,4-oxadiazoles as cathepsin K inhibitors. Bioorg Med Chem Lett16:2909-14 (2006) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cathepsin K |
|---|
| Name: | Cathepsin K |
|---|
| Synonyms: | CATK_HUMAN | CTSK | CTSO | CTSO2 | Cathepsin O | Cathepsin O2 | Cathepsin X |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 36975.68 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P43235 |
|---|
| Residue: | 329 |
|---|
| Sequence: | MWGLKVLLLPVVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIH
NLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVD
YRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGG
YMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVA
RVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGE
NWGNKGYILMARNKNNACGIANLASFPKM
|
|
|
|---|
| BDBM50374296 |
|---|
| n/a |
|---|
| Name | BDBM50374296 |
|---|
| Synonyms: | CHEMBL379622 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H27F3N4O6 |
|---|
| Mol. Mass. | 512.4789 |
|---|
| SMILES | CCC[C@H](NC(=O)C1(CCCCC1)NC(=O)c1ccc(OC(F)(F)F)cc1)C(=O)c1nnc(OC)o1 |
|---|
| Structure | 
|
|---|
Search and Browse
