| Reaction Details |
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 | Report a problem with these data |
| Target | Chymotrypsinogen B |
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| Ligand | BDBM50187800 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_371002 (CHEMBL868500) |
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| Ki | >150000±n/a nM |
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| Citation |  Palmer, JT; Rydzewski, RM; Mendonca, RV; Sperandio, D; Spencer, JR; Hirschbein, BL; Lohman, J; Beltman, J; Nguyen, M; Liu, L Design and synthesis of selective keto-1,2,4-oxadiazole-based tryptase inhibitors. Bioorg Med Chem Lett16:3434-9 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Chymotrypsinogen B |
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| Name: | Chymotrypsinogen B |
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| Synonyms: | A0A2R8YG87_HUMAN | Beta-chymotrypsin | CTRB1 | Chymotrypsin B chain A | Chymotrypsin B chain B | Chymotrypsin B chain C | Chymotrypsinogen B |
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| Type: | PROTEIN |
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| Mol. Mass.: | 27871.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_216634 |
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| Residue: | 263 |
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| Sequence: | MAFLWLLSCWALLGTTFGCGVPAIHPVLSGLSRIVNGEDAVPGSWPWQVSLQDKTGFHFC
GGSLISEDWVVTAAHCGVRTSDVVVAGEFDQGSDEENIQVLKIAKVFKNPKFSILTVNND
ITLLKLATPARFSQTVSAVCLPSADDDFPAGTLCATTGWGKTKYNANKTPDKLQQAALPL
LSNAECKKSWGRRITDVMICAGASGVSSCMGDSGGPLVCQKDGAWTLVGIVSWGSDTCST
SSPGVYARVTKLIPWVQKILAAN
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| BDBM50187800 |
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| n/a |
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| Name | BDBM50187800 |
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| Synonyms: | (S)-ethyl 1-(5-(4-phenethoxybenzyl)-1,2,4-oxadiazol-3-yl)-6-amino-1-oxohexan-2-ylcarbamate | CHEMBL211561 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H32N4O5 |
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| Mol. Mass. | 480.5561 |
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| SMILES | CCOC(=O)N[C@@H](CCCCN)C(=O)c1noc(Cc2ccc(OCCc3ccccc3)cc2)n1 |
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| Structure | 
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