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TargetTryptase
LigandBDBM50411009
Substrate/Competitorn/a
Meas. Tech.ChEMBL_370996
Ki 3.7±n/a nM
Citation Palmer JTRydzewski RMMendonca RVSperandio DSpencer JRHirschbein BLLohman JBeltman JNguyen MLiu L Design and synthesis of selective keto-1,2,4-oxadiazole-based tryptase inhibitors. Bioorg Med Chem Lett 16:3434-9 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Tryptase
Name:Tryptase
Synonyms:Tryptase II | Tryptase beta-1 | Tryptase beta-2 | Tryptase-2
Type:PROTEIN
Mol. Mass.:30518.79
Organism:Homo sapiens (Human)
Description:ChEMBL_210702
Residue:275
Sequence:
MLNLLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCG
GSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGA
DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV
PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAG
VVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKKP
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  Blast E-value cutoff:
BDBM50411009
n/a
NameBDBM50411009
Synonyms:CHEMBL538574
TypeSmall organic molecule
Emp. Form.C26H30Cl2N4O5
Mol. Mass.549.446
SMILESCOCC(=O)N[C@@H](CCCCN)C(=O)c1noc(Cc2ccc(OCCc3ccc(Cl)c(Cl)c3)cc2)n1 |r|
Structure
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