| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Coagulation factor IX |
|---|
| Ligand | BDBM50410995 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_371013 (CHEMBL868511) |
|---|
| Ki | >150000±n/a nM |
|---|
| Citation |  Palmer, JT; Rydzewski, RM; Mendonca, RV; Sperandio, D; Spencer, JR; Hirschbein, BL; Lohman, J; Beltman, J; Nguyen, M; Liu, L Design and synthesis of selective keto-1,2,4-oxadiazole-based tryptase inhibitors. Bioorg Med Chem Lett16:3434-9 (2006) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Coagulation factor IX |
|---|
| Name: | Coagulation factor IX |
|---|
| Synonyms: | Christmas factor | Coagulation factor IX precursor | Coagulation factor IX/VIII | Coagulation factor IXa | Coagulation factor IXa heavy chain | Coagulation factor IXa light chain | F9 | FA9_HUMAN | Factor IX | Factor IXa | Factor IXa (fIXa) | PTC | Plasma thromboplastin component |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 51768.83 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P00740 |
|---|
| Residue: | 461 |
|---|
| Sequence: | MQRVNMIMAESPGLITICLLGYLLSAECTVFLDHENANKILNRPKRYNSGKLEEFVQGNL
ERECMEEKCSFEEAREVFENTERTTEFWKQYVDGDQCESNPCLNGGSCKDDINSYECWCP
FGFEGKNCELDVTCNIKNGRCEQFCKNSADNKVVCSCTEGYRLAENQKSCEPAVPFPCGR
VSVSQTSKLTRAETVFPDVDYVNSTEAETILDNITQSTQSFNDFTRVVGGEDAKPGQFPW
QVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEHNIEETEHTEQKRNVIRII
PHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTNIFLKFGSGYVSGWGRVF
HKGRSALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHEGGRDSCQGDSGGPHVTEVE
GTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT
|
|
|
|---|
| BDBM50410995 |
|---|
| n/a |
|---|
| Name | BDBM50410995 |
|---|
| Synonyms: | CHEMBL536972 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C30H28Cl2F2N4O4 |
|---|
| Mol. Mass. | 617.471 |
|---|
| SMILES | NCCCC[C@H](NC(=O)c1ccc(F)c(F)c1)C(=O)c1noc(Cc2ccc(OCCc3ccc(Cl)c(Cl)c3)cc2)n1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
