| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Alpha-1D adrenergic receptor |
|---|
| Ligand | BDBM50392637 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_412942 (CHEMBL910642) |
|---|
| Ki | 0.51±n/a nM |
|---|
| Citation |  Pallavicini, M; Budriesi, R; Fumagalli, L; Ioan, P; Chiarini, A; Bolchi, C; Ugenti, MP; Colleoni, S; Gobbi, M; Valoti, E WB4101-related compounds: new, subtype-selective alpha1-adrenoreceptor antagonists (or inverse agonists?). J Med Chem49:7140-9 (2006) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Alpha-1D adrenergic receptor |
|---|
| Name: | Alpha-1D adrenergic receptor |
|---|
| Synonyms: | ADA1D_HUMAN | ADRA1A | ADRA1D | Adrenergic receptor | Adrenergic receptor alpha | Alpha 1D-adrenoceptor | Alpha 1D-adrenoreceptor | Alpha adrenergic receptor (1a and 1d) | Alpha-1D adrenoceptor | Alpha-adrenergic receptor 1a | adrenergic Alpha1D |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 60485.82 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | adrenergic Alpha1D ADRA1D HUMAN::P25100 |
|---|
| Residue: | 572 |
|---|
| Sequence: | MTFRDLLSVSFEGPRPDSSAGGSSAGGGGGSAGGAAPSEGPAVGGVPGGAGGGGGVVGAG
SGEDNRSSAGEPGSAGAGGDVNGTAAVGGLVVSAQGVGVGVFLAAFILMAVAGNLLVILS
VACNRHLQTVTNYFIVNLAVADLLLSATVLPFSATMEVLGFWAFGRAFCDVWAAVDVLCC
TASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWVVALVVSVGPLLGWKEPVP
PDERFCGITEEAGYAVFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGVKRERGKAS
EVVLRIHCRGAATGADGAHGMRSAKGHTFRSSLSVRLLKFSREKKAAKTLAIVVGVFVLC
WFPFFFVLPLGSLFPQLKPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQ
CRRRRRRRPLWRVYGHHWRASTSGLRQDCAPSSGDAPPGAPLALTALPDPDPEPPGTPEM
QAPVASRRKPPSAFREWRLLGPFRRPTTQLRAKVSSLSHKIRAGGAQRAEAACAQRSEVE
AVSLGVPHEVAEGATCQAYELADYSNLRETDI
|
|
|
|---|
| BDBM50392637 |
|---|
| n/a |
|---|
| Name | BDBM50392637 |
|---|
| Synonyms: | CHEMBL215421 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H23NO5 |
|---|
| Mol. Mass. | 345.3896 |
|---|
| SMILES | COc1cccc(OC)c1OCCNC[C@H]1COc2ccccc2O1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
