| Reaction Details |
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 | Report a problem with these data |
| Target | Histidine-rich protein PFHRP-II |
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| Ligand | BDBM50121975 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_426926 (CHEMBL909252) |
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| IC50 | 325000±n/a nM |
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| Citation |  Huy, NT; Uyen, DT; Maeda, A; Trang, DT; Oida, T; Harada, S; Kamei, K Simple colorimetric inhibition assay of heme crystallization for high-throughput screening of antimalarial compounds. Antimicrob Agents Chemother51:350-3 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histidine-rich protein PFHRP-II |
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| Name: | Histidine-rich protein PFHRP-II |
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| Synonyms: | HRP1_PLAFA | Histidine-rich protein | Histidine-rich protein PFHRP-II |
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| Type: | PROTEIN |
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| Mol. Mass.: | 35156.49 |
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| Organism: | Plasmodium falciparum |
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| Description: | ChEMBL_500704 |
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| Residue: | 332 |
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| Sequence: | MVSFSKNKVLSAAVFASVLLLDNNNSAFNNNLCSKNAKGLNLNKRLLHETQAHVDDAHHA
HHVADAHHAHHAHHAADAHHAHHAADAHHAHHAADAHHAHHAADAHHAHHAADAHHAHHA
ADAHHAHHAADAHHAHHAADAHHAHHAADAHHAHHAAYAHHAHHASDAHHAADAHHAAYA
HHAHHAADAHHAADAHHAAYAHHAHHAADAHHAADAHHATDAHHAHHAADAHHATDAHHA
ADAHHAADAHHATDAHHAADAHHATDAHHAADAHHAADAHHATDSHHAHHAADAHHAAAH
HATDAHHAAAHHATDAHHAAAHHEAATHCLRH
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| BDBM50121975 |
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| n/a |
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| Name | BDBM50121975 |
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| Synonyms: | (6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2.2.2]oct-2-yl)-methanol | CARDIOQUIN | CHEMBL1294 | CIN-QUIN | DURAQUIN | QUINACT | QUINAGLUTE | QUINALAN | QUINATIME | QUINIDEX | QUINIDINE | QUINORA | US9402878, Quinidine |
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| Type | Small organic molecule |
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| Emp. Form. | C20H24N2O2 |
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| Mol. Mass. | 324.4168 |
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| SMILES | COc1ccc2nccc([C@H](O)[C@H]3C[C@@H]4CCN3C[C@@H]4C=C)c2c1 |r,THB:20:19:12.13:16.15,10:12:18.19:16.15| |
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| Structure | 
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