| Reaction Details |
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 | Report a problem with these data |
| Target | C3a anaphylatoxin chemotactic receptor |
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| Ligand | BDBM50422988 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_438727 (CHEMBL889062) |
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| IC50 | 63±n/a nM |
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| Citation |  Denonne, F; Binet, S; Burton, M; Collart, P; Dipesa, A; Ganguly, T; Giannaras, A; Kumar, S; Lewis, T; Maounis, F; Nicolas, JM; Mansley, T; Pasau, P; Preda, D; Stebbins, K; Volosov, A; Zou, D Discovery of new C3aR ligands. Part 1: arginine derivatives. Bioorg Med Chem Lett17:3258-61 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C3a anaphylatoxin chemotactic receptor |
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| Name: | C3a anaphylatoxin chemotactic receptor |
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| Synonyms: | AZ3B | C3AR | C3AR1 | C3AR_HUMAN | C3R1 | C3a-R | HNFAG09 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53864.66 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_642034 |
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| Residue: | 482 |
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| Sequence: | MASFSAETNSTDLLSQPWNEPPVILSMVILSLTFLLGLPGNGLVLWVAGLKMQRTVNTIW
FLHLTLADLLCCLSLPFSLAHLALQGQWPYGRFLCKLIPSIIVLNMFASVFLLTAISLDR
CLVVFKPIWCQNHRNVGMACSICGCIWVVAFVMCIPVFVYREIFTTDNHNRCGYKFGLSS
SLDYPDFYGDPLENRSLENIVQPPGEMNDRLDPSSFQTNDHPWTVPTVFQPQTFQRPSAD
SLPRGSARLTSQNLYSNVFKPADVVSPKIPSGFPIEDHETSPLDNSDAFLSTHLKLFPSA
SSNSFYESELPQGFQDYYNLGQFTDDDQVPTPLVAITITRLVVGFLLPSVIMIACYSFIV
FRMQRGRFAKSQSKTFRVAVVVVAVFLVCWTPYHIFGVLSLLTDPETPLGKTLMSWDHVC
IALASANSCFNPFLYALLGKDFRKKARQSIQGILEAAFSEELTRSTHCPSNNVISERNST
TV
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| BDBM50422988 |
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| n/a |
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| Name | BDBM50422988 |
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| Synonyms: | CHEMBL230034 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H26N4O4 |
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| Mol. Mass. | 434.4876 |
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| SMILES | [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-c1ccc(o1)-[#6](-c1ccccc1)-c1ccccc1)-[#6](-[#8])=O |
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| Structure | 
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