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TargetD(3) dopamine receptor
LigandBDBM50411693
Substrate/Competitorn/a
Meas. Tech.ChEMBL_465003
Ki 7.94±n/a nM
Citation Micheli FBonanomi GBraggio SCapelli AMCelestini PDamiani FDi Fabio RDonati DGagliardi SGentile GHamprecht DPetrone MRadaelli STedesco GTerreni SWorby AHeidbreder C New fused benzazepine as selective D3 receptor antagonists. Synthesis and biological evaluation. Part one: [h]-fused tricyclic systems. Bioorg Med Chem Lett 18:901-7 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
D(3) dopamine receptor
Name:D(3) dopamine receptor
Synonyms:D2-like dopamine receptor | DOPAMINE D3 | DRD3 | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:n/a
Mol. Mass.:44243.43
Organism:Homo sapiens (Human)
Description:n/a
Residue:400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
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  Blast E-value cutoff:
BDBM50411693
n/a
NameBDBM50411693
Synonyms:CHEMBL270567
TypeSmall organic molecule
Emp. Form.C32H34N8OS
Mol. Mass.578.73
SMILESCc1cc(-c2nc3cc4CCN(CCCSc5nnc(-c6cccc7nc(C)ccc67)n5C)CCc4cc3o2)n(C)n1
Structure
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