| Reaction Details |
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 | Report a problem with these data |
| Target | Mas-related G-protein coupled receptor member X1 |
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| Ligand | BDBM50412988 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_516621 (CHEMBL991397) |
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| EC50 | 20±n/a nM |
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| Citation |  Wroblowski, B; Wigglesworth, MJ; Szekeres, PG; Smith, GD; Rahman, SS; Nicholson, NH; Muir, AI; Hall, A; Heer, JP; Garland, SL; Coates, WJ The discovery of a selective, small molecule agonist for the MAS-related gene X1 receptor. J Med Chem52:818-25 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mas-related G-protein coupled receptor member X1 |
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| Name: | Mas-related G-protein coupled receptor member X1 |
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| Synonyms: | MRGPRX1 | MRGX1 | MRGX1_HUMAN | SNSR3 | SNSR4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36253.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_516621 |
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| Residue: | 322 |
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| Sequence: | MDPTISTLDTELTPINGTEETLCYKQTLSLTVLTCIVSLVGLTGNAVVLWLLGCRMRRNA
FSIYILNLAAADFLFLSGRLIYSLLSFISIPHTISKILYPVMMFSYFAGLSFLSAVSTER
CLSVLWPIWYRCHRPTHLSAVVCVLLWALSLLRSILEWMLCGFLFSGADSAWCQTSDFIT
VAWLIFLCVVLCGSSLVLLIRILCGSRKIPLTRLYVTILLTVLVFLLCGLPFGIQFFLFL
WIHVDREVLFCHVHLVSIFLSALNSSANPIIYFFVGSFRQRQNRQNLKLVLQRALQDASE
VDEGGGQLPEEILELSGSRLEQ
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| BDBM50412988 |
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| n/a |
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| Name | BDBM50412988 |
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| Synonyms: | CHEMBL477008 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H29N5O2 |
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| Mol. Mass. | 479.5729 |
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| SMILES | Cc1c(Cn2ncc(cc2=O)N2CCNCC2)cccc1NC(=O)c1ccc(cc1)-c1ccccc1 |
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| Structure | 
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