| Reaction Details |
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 | Report a problem with these data |
| Target | C5a anaphylatoxin chemotactic receptor (C5aR) |
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| Ligand | BDBM50413240 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_541063 |
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| IC50 | 25.12±n/a nM |
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| Citation |  Sanganee HJ; Baxter A; Barber S; Brown AJ; Grice D; Hunt F; King S; Laughton D; Pairaudeau G; Thong B; Weaver R; Unitt J Discovery of small molecule human C5a receptor antagonists. Bioorg Med Chem Lett 19:1143-7 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C5a anaphylatoxin chemotactic receptor (C5aR) |
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| Name: | C5a anaphylatoxin chemotactic receptor |
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| Synonyms: | C5a anaphylatoxin chemotactic receptor | C5a-R | C5aR | CD_antigen=CD88 |
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| Type: | Enzyme |
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| Mol. Mass.: | 39347.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21730 |
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| Residue: | 350 |
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| Sequence: | MDSFNYTTPDYGHYDDKDTLDLNTPVDKTSNTLRVPDILALVIFAVVFLVGVLGNALVVW
VTAFEAKRTINAIWFLNLAVADFLSCLALPILFTSIVQHHHWPFGGAACSILPSLILLNM
YASILLLATISADRFLLVFKPIWCQNFRGAGLAWIACAVAWGLALLLTIPSFLYRVVREE
YFPPKVLCGVDYSHDKRRERAVAIVRLVLGFLWPLLTLTICYTFILLRTWSRRATRSTKT
LKVVVAVVASFFIFWLPYQVTGIMMSFLEPSSPTFLLLKKLDSLCVSFAYINCCINPIIY
VVAGQGFQGRLRKSLPSLLRNVLTEESVVRESKSFTRSTVDTMAQKTQAV
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| BDBM50413240 |
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| n/a |
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| Name | BDBM50413240 |
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| Synonyms: | CHEMBL471412 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H29FN2O4 |
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| Mol. Mass. | 476.5393 |
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| SMILES | COc1ccc(N(C(C(=O)NC2CCCC2)c2ccccc2F)C(=O)c2ccccc2)c(OC)c1 |
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| Structure | 
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