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TargetC5a anaphylatoxin chemotactic receptor (C5aR)
LigandBDBM50413245
Substrate/Competitorn/a
Meas. Tech.ChEMBL_541063
IC50>100±n/a nM
Citation Sanganee HJBaxter ABarber SBrown AJGrice DHunt FKing SLaughton DPairaudeau GThong BWeaver RUnitt J Discovery of small molecule human C5a receptor antagonists. Bioorg Med Chem Lett 19:1143-7 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
C5a anaphylatoxin chemotactic receptor (C5aR)
Name:C5a anaphylatoxin chemotactic receptor
Synonyms:C5a anaphylatoxin chemotactic receptor | C5a-R | C5aR | CD_antigen=CD88
Type:Enzyme
Mol. Mass.:39347.68
Organism:Homo sapiens (Human)
Description:P21730
Residue:350
Sequence:
MDSFNYTTPDYGHYDDKDTLDLNTPVDKTSNTLRVPDILALVIFAVVFLVGVLGNALVVW
VTAFEAKRTINAIWFLNLAVADFLSCLALPILFTSIVQHHHWPFGGAACSILPSLILLNM
YASILLLATISADRFLLVFKPIWCQNFRGAGLAWIACAVAWGLALLLTIPSFLYRVVREE
YFPPKVLCGVDYSHDKRRERAVAIVRLVLGFLWPLLTLTICYTFILLRTWSRRATRSTKT
LKVVVAVVASFFIFWLPYQVTGIMMSFLEPSSPTFLLLKKLDSLCVSFAYINCCINPIIY
VVAGQGFQGRLRKSLPSLLRNVLTEESVVRESKSFTRSTVDTMAQKTQAV
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50413245
n/a
NameBDBM50413245
Synonyms:CHEMBL469535
TypeSmall organic molecule
Emp. Form.C26H27FN2O5
Mol. Mass.466.5014
SMILESCOc1ccc(N(C(C(=O)NC[C@H](C)O)c2ccccc2F)C(=O)c2ccccc2)c(OC)c1 |r|
Structure
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