| Reaction Details |
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 | Report a problem with these data |
| Target | Cholecystokinin receptor type A |
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| Ligand | BDBM50413477 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_567123 (CHEMBL1030802) |
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| Ki | 173.78±n/a nM |
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| Citation |  Akgün, E; Körner, M; Gao, F; Harikumar, KG; Waser, B; Reubi, JC; Portoghese, PS; Miller, LJ Synthesis and in vitro characterization of radioiodinatable benzodiazepines selective for type 1 and type 2 cholecystokinin receptors. J Med Chem52:2138-47 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cholecystokinin receptor type A |
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| Name: | Cholecystokinin receptor type A |
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| Synonyms: | CCK-A receptor | CCK-AR | CCK1-R | CCKAR | CCKAR_HUMAN | CCKRA | Cholecystokinin receptor | Cholecystokinin receptor type A | Cholecystokinin-1 Receptor |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 47859.34 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Stable expression of human CCK-1 receptors in HEK 293 cells. |
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| Residue: | 428 |
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| Sequence: | MDVVDSLLVNGSNITPPCELGLENETLFCLDQPRPSKEWQPAVQILLYSLIFLLSVLGNT
LVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYF
MGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYS
NLVPFTKNNNQTANMCRFLLPNDVMQQSWHTFLLLILFLIPGIVMMVAYGLISLELYQGI
KFEASQKKSAKERKPSTTSSGKYEDSDGCYLQKTRPPRKLELRQLSTGSSSRANRIRSNS
SAANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTASAERRLSGTPISFILLLSY
TSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGARGEVGEEEEGGTTGASLSRFSYSH
MSASVPPQ
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| BDBM50413477 |
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| n/a |
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| Name | BDBM50413477 |
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| Synonyms: | CHEMBL475226 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H19IN4O2 |
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| Mol. Mass. | 510.327 |
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| SMILES | CN1c2ccccc2C(=N[C@H](NC(=O)Nc2cccc(I)c2)C1=O)c1ccccc1 |r,c:9| |
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| Structure | 
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