| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-3 adrenergic receptor |
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| Ligand | BDBM25392 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_562923 (CHEMBL1019683) |
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| EC50 | 40±n/a nM |
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| Citation |  Procopiou, PA; Barrett, VJ; Bevan, NJ; Biggadike, K; Butchers, PR; Coe, DM; Conroy, R; Edney, DD; Field, RN; Ford, AJ; Guntrip, SB; Looker, BE; McLay, IM; Monteith, MJ; Morrison, VS; Mutch, PJ; Richards, SA; Sasse, R; Smith, CE Synthesis and structure-activity relationships of long-acting beta2 adrenergic receptor agonists incorporating arylsulfonamide groups. J Med Chem52:2280-8 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-3 adrenergic receptor |
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| Name: | Beta-3 adrenergic receptor |
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| Synonyms: | ADRB3 | ADRB3R | ADRB3_HUMAN | B3AR | Beta-2 adrenergic receptor and beta-3 adrenergic receptor | Beta-3 adrenoceptor | Beta-3 adrenoreceptor | adrenergic Beta3 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 43534.88 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 408 |
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| Sequence: | MAPWPHENSSLAPWPDLPTLAPNTANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIV
AIAWTPRLQTMTNVFVTSLAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDVLC
VTASIETLCALAVDRYLAVTNPLRYGALVTKRCARTAVVLVWVVSAAVSFAPIMSQWWRV
GADAEAQRCHSNPRCCAFASNMPYVLLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRG
ELGRFPPEESPPAPSRSLAPAPVGTCAPPEGVPACGRRPARLLPLREHRALCTLGLIMGT
FTLCWLPFFLANVLRALGGPSLVPGPAFLALNWLGYANSAFNPLIYCRSPDFRSAFRRLL
CRCGRRLPPEPCAAARPALFPSGVPAARSSPAQPRLCQRLDGASWGVS
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| BDBM25392 |
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| n/a |
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| Name | BDBM25392 |
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| Synonyms: | 4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;hydrochloride | 4-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,2-diol | 4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}benzene-1,2-diol, 2 | CHEMBL434 | ISOPROTERONOL | Isoprenaline | Isoproterenol | Isoproterenol (-) | Isoproterenol,(+) | Isoproterenol-l | Norisodrine | Novodrin |
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| Type | Small organic molecule |
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| Emp. Form. | C11H17NO3 |
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| Mol. Mass. | 211.2576 |
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| SMILES | CC(C)NCC(O)c1ccc(O)c(O)c1 |
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| Structure | 
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