| Reaction Details |
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 | Report a problem with these data |
| Target | C-X-C chemokine receptor type 3 |
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| Ligand | BDBM50413597 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_497564 (CHEMBL998621) |
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| Ki | 398.11±n/a nM |
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| Citation |  Wijtmans, M; Verzijl, D; van Dam, CM; Bosch, L; Smit, MJ; Leurs, R; de Esch, IJ Exploring a pocket for polycycloaliphatic groups in the CXCR3 receptor with the aid of a modular synthetic strategy. Bioorg Med Chem Lett19:2252-7 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C-X-C chemokine receptor type 3 |
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| Name: | C-X-C chemokine receptor type 3 |
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| Synonyms: | AAO92295.1 | C-X-C chemokine receptor type 3 | C-X-C chemokine receptor type 3 (CXCR3) | C-X-C chemokine receptor type 3 (CXCR3A) | CXCR3 | CXCR3A | CXCR3_HUMAN | GPR9 | chemokine (C-X-C motif) receptor 3 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 40665.65 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 368 |
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| Sequence: | MVLEVSDHQVLNDAEVAALLENFSSSYDYGENESDSCCTSPPCPQDFSLNFDRAFLPALY
SLLFLLGLLGNGAVAAVLLSRRTALSSTDTFLLHLAVADTLLVLTLPLWAVDAAVQWVFG
SGLCKVAGALFNINFYAGALLLACISFDRYLNIVHATQLYRRGPPARVTLTCLAVWGLCL
LFALPDFIFLSAHHDERLNATHCQYNFPQVGRTALRVLQLVAGFLLPLLVMAYCYAHILA
VLLVSRGQRRLRAMRLVVVVVVAFALCWTPYHLVVLVDILMDLGALARNCGRESRVDVAK
SVTSGLGYMHCCLNPLLYAFVGVKFRERMWMLLLRLGCPNQRGLQRQPSSSRRDSSWSET
SEASYSGL
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| BDBM50413597 |
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| n/a |
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| Name | BDBM50413597 |
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| Synonyms: | CHEMBL472421 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H32ClFN2 |
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| Mol. Mass. | 378.954 |
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| SMILES | CC1(C)[C@@H]2CC[C@@]1(C)[C@H](C2)NC1CCN(Cc2ccc(Cl)cc2F)CC1 |r,TLB:10:8:4.5:1| |
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| Structure | 
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