| Reaction Details |
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 | Report a problem with these data |
| Target | Oxytocin receptor |
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| Ligand | BDBM50413707 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_540346 (CHEMBL1025689) |
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| Ki | 39.81±n/a nM |
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| Citation |  Barton, NP; Bellenie, BR; Doran, AT; Emmons, AJ; Heer, JP; Salvagno, CM Discovery and optimisation of a potent and selective tertiary sulfonamide oxytocin antagonist. Bioorg Med Chem Lett19:528-32 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Oxytocin receptor |
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| Name: | Oxytocin receptor |
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| Synonyms: | OT-R | OXTR | OXYR_HUMAN | Oxytocin |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 42793.26 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Oxytocin OXTR HEK293::B2R9L7 |
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| Residue: | 389 |
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| Sequence: | MEGALAANWSAEAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLCLILLLALSGNACV
LLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQV
VGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLATWLGCLVASAPQVHIFSLREV
ADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAA
AEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVW
DANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGRRLGET
SASKKSNSSSFVLSHRSSSQRSCSQPSTA
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| BDBM50413707 |
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| n/a |
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| Name | BDBM50413707 |
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| Synonyms: | CHEMBL515384 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H18N4O3S2 |
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| Mol. Mass. | 438.523 |
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| SMILES | COc1ccc(cn1)N(Cc1nc(cs1)-c1ccccc1)S(=O)(=O)c1ccccn1 |
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| Structure | 
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